Genome Engineering Technologies for Diseases
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular Genetics and Genetic Diseases".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 10
Special Issue Editor
Interests: transposon; random screening; gene editing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Recent advances in genome engineering technologies have opened up new avenues for exploring gene function and developing innovative approaches to understanding and treating human diseases. Techniques such as gene editing, gene delivery, and insertional mutagenesis have enabled researchers to manipulate the genome with increasing precision and efficiency, driving advances in both basic and translational biomedical research.
These technologies are also fueling progress in functional genomics through the development of cell-based assays, reporter systems, and in silico tools that facilitate the large-scale analysis of gene regulatory networks and disease-related pathways. Alongside these advances, a variety of functional modules have been identified—elements that contribute to enhancing the versatility and applicability of genome editing platforms.
Genome engineering is also playing a growing role in the development of advanced therapeutic strategies, such as cell therapy and personalized immunotherapy, including CAR-T cells. The integration of experimental and computational methods continues to expand our ability to model diseases and evaluate candidate interventions at the cellular level.
This Special Issue will showcase recent developments in genome engineering technologies and their diverse applications in disease research. We welcome original research articles and reviews addressing tool development, computational analysis, functional innovation, and therapeutic applications.
Dr. Kosuke Ishikawa
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- genome engineering
- gene editing
- gene delivery
- transposable elements
- insertinal mutagenesis
- functional genomics
- in silico analysis
- cell-based assays
- disease modeling
- cell therapy
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