Rheumatic Diseases: From Pathophysiology to Current and Emerging Therapeutic Approaches
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Immunology and Immunotherapy".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 46
Special Issue Editor
2. Deutsches Zentrum für Immuntherapie (DZI), Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
Interests: rheumatic disease; rheumatoid arthritis; artificial intelligence
Special Issue Information
Dear Colleagues,
Rheumatic diseases represent a complex group of conditions, challenging clinicians in their etiology, diagnosis, and therapy. These often-chronic illnesses, rooted in diverse autoimmune and inflammatory processes, necessitate a sophisticated understanding of their underlying pathophysiology for effective management. Gaining deeper insights into the specific autoimmune mechanisms, such as the dysregulation of T- and B-lymphocytes, cytokine storms, and autoantibody production, allows for more accurate disease differentiation and the development of targeted therapies. Significant progress has been made with current treatments, including traditional DMARDs (Disease-Modifying Anti-Rheumatic Drugs) and biologics. However, the field is being rapidly revolutionized by emerging therapeutic approaches. Notably, the innovative use of CAR T-cell therapy offers the potential for substantially improved clinical outcomes, potentially leading to long-term remission or even cure in some rheumatic diseases. Furthermore, digitalization is rapidly increasing in rheumatology. New digital technologies are simplifying diagnostic workflows, enhancing the quality of care, and making patient monitoring and disease surveillance more efficient and accessible, supporting both patients and healthcare providers. The broad scope of this Special Issue will allow researchers to include a wide variety of studies on these conditions.
Dr. Harriet Morf
Guest Editor
Manuscript Submission Information
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Keywords
- rheumatic diseases
- molecular mechanisms
- treatment
- artificial intelligence
- cytokine
- anti-rheumatic drugs
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