Chronic Vascular Impairment in Heart, Brain, and Kidney Disorders: Molecular Mechanisms and Therapeutic Strategies
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 6
Special Issue Editor
Interests: atherosclerosis; lipoprotein; inflammation; antioxidants; oxidative stress; cardiovascular diseases; neurodegenerative disorders, laboratory medicine and analytical method validation; nutrition and population health
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cardiovascular, neurodegenerative, and renal disorders are increasingly recognized as sharing common vascular pathologies that compromise organ function and accelerate disease progression. Vascular impairment including endothelial dysfunction, blood–brain barrier disruption, glomerular injury, and microvascular rarefaction plays a central role in the pathogenesis of heart, brain, and kidney diseases. This Special Issue explores the molecular and cellular mechanisms underlying vascular dysfunction in conditions such as heart failure, stroke, Alzheimer's disease, chronic kidney disease, and vascular dementia. Key themes include the role of oxidative stress, inflammation, lipid signaling, and endothelial–mesenchymal transition in driving vascular pathology across these organ systems. Additionally, the issue highlights emerging therapeutic strategies aimed at preserving or restoring vascular integrity ranging from pharmacological interventions and lifestyle-based approaches to novel gene and cell therapies. By integrating insights from cardiovascular, neurovascular, and renal research, this collection aims to foster a more unified understanding of systemic vascular health and promote translational advances in the treatment of complex multi-organ disorders.
Dr. Mahdi O. Garelnabi
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- atherosclerosis
- lipoprotein
- inflammation
- antioxidants
- oxidative stress
- cardiovascular diseases
- neurodegenerative disorders
- blood–brain barrier
- stroke
- Alzheimer's disease
- kidney
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
