Roles of Extracellular Vesicles in Health and Diseases
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 111
Special Issue Editors
2. Department of Surgery, Wexner Medical Center, The Ohio State University, Columbus, OH 43212, USA
Interests: EVs in liver pathology; therapeutic roles of stem cell EVs; role of hepatocyte EVs in alcohol-associated liver disease (AALD) and metabolic dysfunction-associated fatty liver disease (MAFLD)
Special Issues, Collections and Topics in MDPI journals
Interests: EVs in liver fibrosis in AALD; MAFLD and Fontan-associated liver disease (FALD); mechanisms underlying therapeutic actions of hepatocyte EVs; analysis and functional roles of EV molecular payload components
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Extracellular vesicles (EVs) are nano-sized membrane particles that contain a complex molecular cargo comprising RNA, microRNA, protein, and lipids. EVs have become recognized for their pivotal roles in intercellular communication because they are released into the interstitial space and can then bind to neighboring cells or be transported in bodily fluids to recipient cells at distant sites. After binding to target cells, EVs may deliver their molecular cargo, resulting in transcriptional, functional, and/or and phenotypic changes in cells according to the bioactive components received.
This Special Issue seeks literature reviews or original primary research papers regarding the regulation of cellular homeostasis in any cell, tissue, or organ system, and the contribution of EVs from mammalian or bacterial sources to pathogenesis or therapeutics.
Dr. David R. Brigstock
Dr. Xinlei Li
Guest Editors
Manuscript Submission Information
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Keywords
- extracellular vesicle
- exosome
- pathogenesis
- therapy
- cancer
- neurodegenerative diseases
- pulmonary diseases
- cardiovascular diseases
- inflammatory diseases
- infectious diseases
- kidney diseases
- gastrointestinal diseases
- aging
- diabetes
- autoimmune disorders
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