Organoids in Biomedical Research

Dear Colleagues,

Organoids are three-dimensional (3D) self-organized in vitro replicas of specific organs or tissues. These miniature structures can be generated from either human pluripotent stem cells or adult stem cells derived from healthy individuals or patients. Three-dimensional organoids represent a compelling new class of biological models because they resemble the original organs and carry genetic information that can recapitulate human (patho)physiology. Therefore, organoids carry great promise for biomedical research because they can be utilized for various applications, such as preclinical drug testing, personalized and regenerative medicine, gene repair and transplantation. Extensive research is currently being conducted to generate various types of organoids, including brain, retinal, cardiac, intestinal and many others.

This Special Issue, “Organoids in Biomedical Research”, aims to provide the latest insights into the generation, characterization, and application of 3D organoids as human models for biomedical research. The main focus will be on brain and retinal organoids to model neurodegenerative and retinal diseases.

Dr. Ahmad Salti
Guest Editor

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