Recent Research on Dry Eye

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 391

Special Issue Editor


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Guest Editor
Department of Optometry and Vision Science, Jerusalem Multidisciplinary College, Jerusalem, Israel
Interests: anterior segment; contact lenses; complications in contact lenses; dry eye; MGD; digital eye strain; demodex; blepharitis

Special Issue Information

Dear Colleagues,

This Special Issue aims to explore the latest advancements in our understanding of the pathophysiology of dry eye, including risk and protective factors, and possible therapeutic solutions. We invite submissions that cover a broad range of topics, including but not limited to the biochemical changes in tear film composition, innovative diagnostic techniques, and novel therapeutic interventions.

Our goal is to compile a collection of high-quality research articles, reviews, and brief reports that not only deepen our understanding of these conditions but also contribute to the development of effective strategies for prevention, diagnosis, and treatment. We encourage contributions from researchers whose work helps bridge the gap between basic science and clinical practice in the study of dry eye.

We look forward to your submissions, advancing our knowledge of these increasingly prevalent conditions, which have significant implications for ocular and general health worldwide.

Warm regards,

Dr. Liat Gantz
Guest Editor

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Keywords

  • dry eye
  • meibomian gland dysfunction
  • ocular surface disease

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Published Papers (1 paper)

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Research

16 pages, 3287 KiB  
Article
Evaluating Magnetic Stimulation as an Innovative Approach for Treating Dry Eye Disease: An Initial Safety and Efficacy Study
by Hadas Ben-Eli, Shimon Perelman, Denise Wajnsztajn and Abraham Solomon
Biomedicines 2025, 13(5), 1064; https://doi.org/10.3390/biomedicines13051064 - 28 Apr 2025
Viewed by 230
Abstract
Objective: The aim of this study was to assess the safety and preliminary efficacy of repetitive magnetic stimulation (RMS) as a treatment intervention for dry eye disease (DED), focusing on symptom reduction. Methodology: This investigation involved 22 adult participants (85% females, aged between [...] Read more.
Objective: The aim of this study was to assess the safety and preliminary efficacy of repetitive magnetic stimulation (RMS) as a treatment intervention for dry eye disease (DED), focusing on symptom reduction. Methodology: This investigation involved 22 adult participants (85% females, aged between 22 and 79 years) diagnosed with moderate-to-severe DED. These individuals were subjected to RMS treatment targeting one or both eyes using the VIVEYE-Ocular Magnetic Neurostimulation System version 1.0 (Epitech-Mag LTD; National Institute of Health (NIH) clinical trials registry #NCT03012698). A placebo-controlled group was also included for comparative analysis, with all subjects being monitored over a three-month period. The evaluation of safety encompassed monitoring changes in best corrected visual acuity, ocular pathology, and the reporting of adverse events. Participant tolerance was gauged through questionnaires, measurements of intraocular pressure (IOP), Schirmer’s test, and vital signs. The efficacy of the treatment was assessed by comparing pre- and post-treatment scores for fluorescein staining (according to National Eye Institute (NEI) grading) and patient-reported outcomes. Results: No statistically significant changes were found in visual acuity, IOP, or Schirmer’s test results between the RMS-treated and control groups (p < 0.05), indicating that RMS does not negatively impact these ocular functions. However, RMS treatment was associated with improved tear film stability (p = 0.19 vs. p = 0.04) and corneal health (p = 0.52 vs. p = 0.004), with no improvements in the control group. Initial symptom improvement was observed in both RMS-treated and placebo groups (p = 0.007 vs. p = 0.008), suggesting a potential therapeutic benefit of RMS for ocular surface conditions beyond a placebo effect. Conclusions: This study presents RMS as a promising therapeutic approach for DED, highlighting its potential to promote corneal epithelial repair, enhance tear film stability, and improve patient-reported symptoms without negatively impacting IOP, visual acuity, or tear production. This confirms the safety and suggests the efficacy of RMS therapy for dry eye conditions. Full article
(This article belongs to the Special Issue Recent Research on Dry Eye)
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