Molecular Research in Obesity
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Endocrinology and Metabolism Research".
Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 11534
Special Issue Editors
Interests: obesity; bariatric surgery; leukocytes; oxidative stress; metabolic pathways
Special Issues, Collections and Topics in MDPI journals
Interests: obesity; metabolic disorders; inflammation; oxidative stress; mitochondrial dysfunction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Obesity is a complex chronic disease of epidemic proportions, contributing to the increasing burdens of cardiovascular disease, type 2 diabetes, hyperlipidemia, and premature death worldwide. Although the rapid increase in obesity has been driven by environmental changes, genetic factors are also critical players in determining individual predisposition to this condition.
Obesity has been linked to adverse alterations in adipose tissue, specifically white and brown adipose tissue, that predisposes subjects to metabolic dysregulation, chronic low-grade inflammation, and dysfunction in energy storage and expenditure. These adverse alterations include the activation and/or inhibition of relevant molecular pathways regulating appetite, metabolism, energy balance, adipocyte differentiation, and thermogenesis. Although mechanisms beyond obesity and its related comorbidities have been extensively investigated, some of them have yet to be fully elucidated.
This Special Issue aims to summarize the current knowledge and advances in this field, showcasing the novel molecular mechanisms underlying obesity; to prevent the individual risk of developing obesity; and to identify novel approaches in the management of this condition.
Original research articles and reviews include (but are not limited to): elucidating the molecular underpinnings of obesity, identifying genetic factors, unraveling metabolic pathways, and exploring the functions of adipose tissue.
Dr. Zaida Abad-Jiménez
Dr. Teresa Vezza
Guest Editors
Manuscript Submission Information
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Keywords
- obesity
- genetics
- molecular pathways
- adipose tissue
- metabolism
- leukocytes
- prevention
- new targets for treatment
- translational studies
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