Advances in Pheochromocytoma and Paraganglioma 2.0
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 293
Special Issue Editor
Interests: pheochromocytoma; paraganglioma; signaling pathways; genetics; metabolomics; targeted therapies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Pheochromocytoma and Paraganglioma (PPGL) are rare neuroendocrine characterized by catecholamine secretion which are responsible for alterations in basically all organ systems. These tumors also bear, so far unpredictable, potential to metastasize, even years after the primary tumor was found and removed. Undiagnosed and untreated PPGLs are associated with high morbidity and mortality, mainly due to cardiovascular complications. Recent years lead to significant progress in the genetics, pathogenesis, and metabolomics of PPGLs, which, in turn, allows for the development of novel diagnostic and therapeutic methods. However, the only curative treatment available is the complete surgical resection, which is not an option for metastatic disease and non-resectable tumors. Therefore, the diagnosis and treatment of metastatic PPGL represents a major health concern and is the main focus of researchers.
The journal Biomedicines is launching the Special Issue on Advances in Pheochromocytoma and Paraganglioma. Reviews or original articles dealing with the genetic, biochemical, and molecular aspects associated with PPGL, pathogenesis in experimental models and humans, as well as articles providing an up-to-date overview of the use of circulating/tissue biomarkers in early diagnosis and management of PPGL and metastatic disease are particularly welcome. In addition, we warmly invite you to submit articles reporting on evidence and expectations from innovative and personalized treatments.
Dr. Ivana Jochmanová
Guest Editor
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Keywords
- pheochromcytoma
- paraganglioma
- metastatic disease
- genetics
- pathogenesis
- diagnosis
- biomarkers
- targeted therapy
- personalized medicine
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Related Special Issue
- Advances in Pheochromocytoma and Paraganglioma in Biomedicines (5 articles)
