Special Issue "Differential Gene Expression and Coexpression"

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Bioinformatics".

Deadline for manuscript submissions: 31 October 2021.

Special Issue Editors

Dr. Ioannis Michalopoulos
Website1 Website2
Guest Editor
Centre of Systems Biology, Biomedical Research Foundation, Academy of Athens, 4 Soranou Efesiou, Athens 11527, Greece
Interests: genomics; transcriptomics; epigenomics; proteomics; structural bioinformatics; phylogenomics; radiogenomics; cytogenetics and pharmacogenomics
Dr. Apostolos Malatras
Guest Editor
CY-Biobank, Centre of Excellence in Biobanking and Biomedical Research, University of Cyprus, Nicosia, Cyprus
Interests: Bioinformatics; Transcriptomics; Genomics; NGS; Biobanking

Special Issue Information

Dear Colleagues,

The most common approach in transcriptomics (RNA-seq and microarrays) is differential gene expression analysis. Genes identified as differentially expressed may be responsible for phenotype differences between various biological conditions. An alternative approach is gene co-expression analysis, which detects groups of genes with similar expression patterns across unrelated sets of transcriptomic data of the same organism. Co-expressed genes tend to be involved in similar biological processes. This Special Issue will include reviews and research articles on the topic differential gene expression and coexpression. The reviews will provide an overview of the methods available for transcriptomic analysis, while the research articles will provide an in-depth description of each state-of-the-art tool. Please send me an abstract prior to submission to make sure that your work falls within the scope of this Special Issue.

Dr. Ioannis Michalopoulos
Dr. Apostolos Malatras
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • transcriptomics
  • differential gene expression
  • gene co-expression
  • RNA-seq
  • microarrays
  • gene networks
  • bioinformatics tools

Published Papers

This special issue is now open for submission.
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