Multidisciplinary Insights on Bone Healing

At the basis of the bone healing process there is a sophisticated multifactorial “system” composed of both macro- and microscopic agents that interact each other in order to obtain a recovery of the correct morphological and functional features. Bone-tissue-specific agents and extra-bone factors can influence the final outcome at several levels; all of them are characterized by complex and multidisciplinary perspectives that have raised many questions that have yet to be fully elucidated. The consequence has been the raising of the curtain on this fascinating topic, which must be looked at from different angles in order to be correctly framed.

Basic research with a transitional approach and clinical applications about the bone healing process are manifold: fracture can be either iatrogenic (antiresorptive therapies) or spontaneous, involving a healthy or an impaired bone; moreover, adequate bone healing of osteotomic surfaces is essential in several surgical specialties. Interdisciplinarity between pre-clinical (e.g., the interaction of tissue and biophysical energy), medical (e.g., innovative pharmacological protocols) and surgical specialties, as well as regenerative medicine strategies, may result in a common enrichment in terms of knowledge of bone healing processes and an improvement in applying these notions for the safety of patients. We hope that researchers with different areas of expertise will consider contributing to this Special Issue.

Dr. Alexandre Anesi
Dr. Francesco Cavani
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.