Molecular Mechanisms behind the Wnt Signalling Pathways

Dear Colleagues,

The Wnt signalling pathways underpin embryonic and organ development as well as tissue homeostasis. The dysregulation of these pathways, in particular, the b-catenin-dependent pathway, can result in oncogenesis and impaired stem-cell function. Accordingly, Wnt-signalling-pathway components are of interest as potential therapeutic targets in the treatment of cancer and in molecular biotechnological applications. The aim of this Special Issue is to provide a contemporary update on the latest studies of these fascinating pathways.

In this Special Issue, we welcome the following submissions:

• Original research articles investigating molecular, cellular, and preclinical studies on Wnt signalling;
• Reviews covering recent studies of Wnt signalling and its relevance to specific aspects of biology;
• Technical reports detailing new in silico, in vitro, and in vivo methodologies for the study of Wnt signalling in diseases and biotechnology;
• Opinions and perspectives covering new hypotheses on Wnt signal transduction and the role of Wnt signalling in mediating specific cellular and whole-organ developmental processes.

We look forward to receiving your contributions. 

Dr. Mark Agostino
Dr. Sebastian Other-Gee Pohl
Guest Editors

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