Pathophysiology of Spinal Cord Injury (SCI)

Dear Colleagues,

Spinal cord injury (SCI) leads to paralysis, sensory, and autonomic nervous system dysfunctions. However, the pathophysiology of SCI is complex, not limited to the nervous system. Indeed, several other organs and tissue are also affected by the injury, directly or not, acutely or chronically, which induces numerous health complications. While a lot of research has been performed to repair motor and sensory functions, SCI-induced health issues are less studied, although they represent a major concern among patients. There is a gap of knowledge in pre-clinical models studying these SCI-induced health complications that limits translational applications in humans.

In this Special Issue of Biology, we encourage the submission of manuscripts on any aspects of the pathophysiology of spinal cord injuries. This includes, but is not limited to, the impact of SCI on cardiovascular function, bladder and bowel function, risk of infections associated with SCI, liver pathology, metabolic syndrome, bones and muscles loss, and cognitive functions. We welcome original research articles, review articles, and short communications. This Special Issue will provide an overview of the pre-clinical models available to study the pathophysiology of SCI, and bring experts in the field to discuss what is needed to increase the research and translational potential of SCI-induced health complications.

Dr. Cédric G. Geoffroy
Dr. Warren Alilain
Guest Editors

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