How the Timing of Biological Processes is Controlled and Modified at the Molecular and Cellular Level?

Dear Colleagues,

The correct timing of molecular and cellular events is critical for embryo development, cell/tissue homeostasis, and functions in all organisms. One of the examples is the temporal regulation of cell cycle events. The cell cycle has to proceed in a well-defined time frame to assure, for example, the coordination between cell proliferation and the embryo developmental program. The checkpoint mechanisms monitor if the necessary processes have been completed before starting the new ones. Thus, the precise timely coordination between molecular pathways and their specific regulation in different conditions allows the harmonious functioning of cells, tissues, and organs. Another example is a circadian rhythm, which refers to any biological process occurring with about 24 hours oscillation. Because all aspects of cell physiology require a precise time control the defects in this control may contribute to a number of diseases, including cancers, diabetes, and metabolic or behavioral disorders, and well beyond.
For this Special Issue, we invite research articles and review articles on all aspects of temporal regulation in cells and tissues, and particularly those, which contribute to our understanding of the role of the time-dependent coordination between molecular pathways in physiological vs. pathological conditions. We hope that the colleagues from many different fields of biology and medicine in which the “How the timing of biological processes is controlled and modified at the molecular and cellular level?” will contribute to this Special Issue. 

Prof. Dr. Jacek Z Kubiak
Prof. Dr. Malgorzata Kloc
Guest Editors

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