Special Issue "Genome Regulation and Evolutionary Transitions in Animals"

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Genetics and Genomics".

Deadline for manuscript submissions: 30 November 2021.

Special Issue Editors

Prof. Dr. Wojciech Makalowski
E-Mail Website
Guest Editor
Institute of Bioinformatics, University Münster, 48149 Munster, Germany
Interests: evolutionary genomics; transposable elements; bioinformatics software development
Dr. Victoria Shabardina
E-Mail Website
Guest Editor
Institute of Evolutionary Biology, UPF-CSIC, Barcelona, Spain
Interests: protein evolution; paralogous genes’ fate; multicellularity origin in animals

Special Issue Information

Dear Colleagues,

The advances in molecular techniques and bioinformatics methods in recent decades have opened up new possibilities for understanding mechanisms of genome evolution. This, in turn, has allowed for a better insight into how genome structure and regulation conditioned appearance of complex structures and novel or modified physiological functions in the history of life. The role of distant regulatory elements, repetitive elements, long non-coding regions, and genome and gene duplications has been acknowledged as determining factors in animal evolution. Nevertheless, the link between molecular evolution and phenotypic change is one of the least understood phenomena in biology and, at the same time, the question most desired to be answered. How do mutations provide flexibility to an organism to adapt to environmental changes or to fit to a new ecological niche? How does genome reorganization unfold new levels of expression regulation and biochemical interactions in the cells? What mechanisms underlie modifications or emergence of new organs during embryo development? This Special Issue invites original research papers and reviews that provide more details on the topic and contribute to our understanding of how animal body and physiology have originated and evolved.

Prof. Dr. Wojciech Makalowski
Dr. Victoria Shabardina
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • genome evolution
  • phenotypic novelties
  • origin of animals
  • lifestyle adaptation
  • environmental adaptation

Published Papers

This special issue is now open for submission.
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