Pathogens-Host Interaction and Vaccine/Drug Design
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Medical Biology".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 1110
Special Issue Editor
Interests: the structural biology of infectious diseases; bacterial; pathogens and their elicited immune responses
Special Issue Information
Dear Colleagues,
Over the last century, improvements in prevention and treatments have resulted in a significant drop in death rates from infectious diseases. However, the recent COVID-19 pandemic proved that there is an urgent need for global efforts to develop effective strategies for prevention, early detection and the development of therapeutics for infectious agents. Currently, infectious diseases remain among the top ten leading causes of death worldwide, with COVID-19 and other respiratory infections resulting in over 11 million deaths in 2021 alone.
When a pathogen enters the host organism, it is confronted by a network of specialized host cells and molecules aiming to detect and eliminate invading pathogens. In response, pathogens have evolved multiple strategies for evading, modulating and hijacking host immune responses. This complex interplay between the host organism and pathogens, including viruses, bacteria and parasites, is referred to as host–pathogen interactions.
Enhancing our knowledge of the mechanisms pathogens use to invade and multiply within hosts and evade immune defenses is essential for understanding infectious diseases. Comprehending host–pathogen interactions will enable the identification of immune correlates of protection, potential therapeutic targets, and the development of novel treatments.
For this Special Issue, we invite researchers to contribute either original research (both in vivo or in vitro studies) or review articles focusing on the molecular basis of pathogen–host interactions and the design of novel therapeutics.
Dr. Iga Kucharska
Guest Editor
Manuscript Submission Information
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Keywords
- infectious diseases
- host–pathogen interactions
- vaccine
- drug design
- immune evasion
- immunogen
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