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Bioengineering
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Translational Advances in Dental Implants
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Translational Advances in Dental Implants

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: closed (20 April 2025) | Viewed by 5055

Special Issue Editors

Dr. Roy Judge

E-Mail Website
Guest Editor
Melbourne Dental School, University of Melbourne, Parkville, VIC 3010, Australia
Interests: bone mechanics; complication mechanisms; prosthodontics; implant design; clinical trials; complications in practice; bioactive surfaces; biomechanics; overload
Dr. Vinicius Rosa

E-Mail Website
Guest Editor
Faculty of Dentistry, National University of Singapore, 9 Lower Kent Ridge Road, Singapore 119085, Singapore
Interests: graphene; coatings; tissue engineering; dental material; induced pluripotent stem cells; differentation; biocompatibility

Special Issue Information

Dear Colleagues,

The advent of dental implants has been a true game changer for the management of patents with oral tissue loss. As with many successful treatment strategies, there is an ongoing revision of the protocols of materials and strategies to improve patient outcomes. The opportunities for advancement include stem cell applications, surface treatments, novel implants, and prosthodontic configurations, as well digital design and manufacture. A multifaceted evolution of implant therapy must be fully reported, as per this special decision of bioengineering. Based on long-term success and high patient uptake research, teams have significant scope to showcase their evidence base for advancing this pivotal aspect of oral rehabilitation. This Special Issue will summarize new research associated with the advancement of dental implant care.

Dr. Roy Judge
Dr. Vinicius Rosa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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Published Papers (3 papers)

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Research

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20 pages, 7387 KiB  
Article
Press-Fit Placement of a Rectangular Block Implant in the Resorbed Alveolar Ridge: Surgical and Biomechanical Considerations
by Efthimios Gazelakis, Roy B. Judge, Joseph E. A. Palamara, Shiva Subramanian and Mohsin Nazir
Bioengineering 2024, 11(6), 532; https://doi.org/10.3390/bioengineering11060532 - 23 May 2024
Viewed by 1567
Abstract
Rectangular Block Implant (RBIs) were manufactured, using computer-aided-design lathe turning, surface roughened with grit blasting and gamma irradiated. Implants were surgically placed into the resorbed edentulous mandibular ridges of both greyhound dogs (ex vivo and in vivo) and humans; the pooled total was [...] Read more.
Rectangular Block Implant (RBIs) were manufactured, using computer-aided-design lathe turning, surface roughened with grit blasting and gamma irradiated. Implants were surgically placed into the resorbed edentulous mandibular ridges of both greyhound dogs (ex vivo and in vivo) and humans; the pooled total was 17 placements. The aim was to achieve mechanical stability and full implant submergence without damage to the mandibular canal and without bone fracture: fulfilment of all of these criteria was deemed to be a successful surgical outcome. Rectangular osteotomy sites were prepared with piezo surgical instrumentation. Sixteen implants were fully submerged and achieved good primary stability without bone fracture and without evidence of impingement of the mandibular canal. One implant placement was deemed a failure due to bone fracture: the event of a random successful outcome was rejected (p < 0.01 confidence, binomial analysis). Technique of placement yielded excellent mechanical retention: key biomechanical factors that emerged in this process included under preparation of the osteotomy site with the use of specifically designed trial-fit gauges, the viscoelastic property of the peri-implant bone, the flat faces and cornered edges of the block surfaces which enhance stress distribution and mechanical retention, respectively. It was concluded that the surgical protocol for the RBI placement in the resorbed alveolus is a predictable clinical procedure tailored to its specific, unique biomechanical profile. Full article
(This article belongs to the Special Issue Translational Advances in Dental Implants)
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13 pages, 2609 KiB  
Article
The 3D Printing and Evaluation of Surgical Guides with an Incorporated Irrigation Channel for Dental Implant Placement
by Robert-Angelo Tuce, Monica Neagu, Vasile Pupazan, Adrian Neagu and Stelian Arjoca
Bioengineering 2023, 10(10), 1168; https://doi.org/10.3390/bioengineering10101168 - 7 Oct 2023
Cited by 5 | Viewed by 2379
Abstract
Dental implant insertion requires the preparation of the implant bed via surgical drilling. During this stage, irrigation is essential to avoid thermal damage to the surrounding bone. Surgical guides enhance the accuracy of the implant site preparation, but they mask the drilling site, [...] Read more.
Dental implant insertion requires the preparation of the implant bed via surgical drilling. During this stage, irrigation is essential to avoid thermal damage to the surrounding bone. Surgical guides enhance the accuracy of the implant site preparation, but they mask the drilling site, hampering coolant delivery. A variety of designs are aimed at improving the coolant access to the target site. Using standard dental implant simulation software, this paper presents an in-house design and 3D printing workflow for building surgical guides that incorporate a coolant channel directed toward the entry point of the burr. The proposed design was evaluated in terms of the bone temperature elevations caused by drilling performed at 1500 rpm, under an axial load of 2 kg, and irrigation with 40 mL/min of saline solution at 25 °C. Temperature measurements were performed on porcine femoral pieces, in the middle of the cortical bone layer, at 1 mm from the edge of the osteotomy. The mean temperature rise was 3.2 °C for a cylindrical sleeve guide, 2.7 °C for a C-shaped open-sleeve guide, and 2.1 °C for the guide with an incorporated coolant channel. According to a one-way ANOVA, the differences between these means were marginally insignificant (p = 0.056). The individual values of the peak temperature change remained below the bone damage threshold (10 °C) in all cases. Remarkably, the distribution of the recorded temperatures was the narrowest for the guide with internal irrigation, suggesting that, besides the most effective cooling, it provides the most precise control of the intraosseous temperature. Further studies could test different design variants, experimental models (including live animals), and might involve computer simulations of the bone temperature field. Full article
(This article belongs to the Special Issue Translational Advances in Dental Implants)
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Review

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14 pages, 1208 KiB  
Review
Zirconia in Dental Implantology: A Review of the Literature with Recent Updates
by Sami Aldhuwayhi
Bioengineering 2025, 12(5), 543; https://doi.org/10.3390/bioengineering12050543 - 19 May 2025
Viewed by 37
Abstract
Zirconia dental implants have emerged as a transformative material in implantology, offering a biocompatible, esthetic, and durable alternative to traditional titanium implants. This comprehensive review explores the key properties of zirconia, including high fracture resistance, esthetic superiority, and low bacterial affinity. The ability [...] Read more.
Zirconia dental implants have emerged as a transformative material in implantology, offering a biocompatible, esthetic, and durable alternative to traditional titanium implants. This comprehensive review explores the key properties of zirconia, including high fracture resistance, esthetic superiority, and low bacterial affinity. The ability of zirconia to integrate with bone through osseointegration, coupled with its resistance to plaque and inflammation, results in a product that is particularly suitable for patients with metal sensitivities or high esthetic demands. However, challenges such as brittleness and complex manufacturing processes persist. Advances in surface modification techniques and material optimization are poised to address these limitations, paving the way for broader applications. The purpose of this descriptive review was to emphasize the mechanical, antibacterial, osteointegration and survival rates of zirconia implants. This paper also summarizes findings from recent empirical studies, highlighting zirconia’s clinical performance, biological responses, and future potential as a mainstream implant material. Full article
(This article belongs to the Special Issue Translational Advances in Dental Implants)
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