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Bioengineering
Special Issues
Bioinspired and Biogenic Materials for Biomedical and Bioengineering Applications
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Bioinspired and Biogenic Materials for Biomedical and Bioengineering Applications

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: closed (31 August 2024) | Viewed by 4256

Special Issue Editor

Dr. Xiang Ma

E-Mail Website
Guest Editor
Department of Biochemistry, Grand View University, Des Moines, IA 50316, USA
Interests: bio-inspired materials; self-assembly; biosensing; drug delivery; machine learning
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nature has provided incredible sources for biogenic materials and inspiration for the design of novel bioinspired materials for various applications in biomedicine and bioengineering. Such applications include the development of unique optical, sensing, electronic and structural materials and devices, biofunctional surface coatings, bioimaging, drug delivery, tissue regeneration, and theory and computation applications.

This Special Issue seeks to showcase research papers, short communications, and comprehensive review articles that deal with cutting-edge experimental and computational methodologies for applications of bioinspired and biogenic materials in the field of biomedicine and bioengineering. Topics of interest for this Special Issue include, but are not limited to, the following:

  • Fabrications of optical, sensing, electronic and structural devices based on bioinspired and biogenic materials;
  • Biomaterials for the delivery of therapeutic and biological cues;
  • Bioinspired materials and their immunomodulatory interactions;
  • Antimicrobial surface coatings;
  • Novel design of biomaterials for tissue regeneration;
  • Bioinspired and biogenic materials for bioimaging;
  • Theoretical and computational guidance for the design of biomaterials and devices, including machine learning applications in biomedicine and bioengineering;

It is my pleasure to invite you to submit a manuscript for this Special Issue. We look forward to receiving your submissions!

Dr. Xiang Ma
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioinspired
  • biogenic
  • biomedicine
  • bioengineering
  • theory
  • computation

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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29 pages, 4014 KiB  
Article
Characterization of Amnion-Derived Membrane for Clinical Wound Applications
by Alison L. Ingraldi, Tim Allen, Joseph N. Tinghitella, William C. Merritt, Timothy Becker and Aaron J. Tabor
Bioengineering 2024, 11(10), 953; https://doi.org/10.3390/bioengineering11100953 - 24 Sep 2024
Viewed by 1466
Abstract
Human amniotic membrane (hAM), the innermost placental layer, has unique properties that allow for a multitude of clinical applications. It is a common misconception that birth-derived tissue products, such as dual-layered dehydrated amnion–amnion graft (dHAAM), are similar regardless of the manufacturing steps. A [...] Read more.
Human amniotic membrane (hAM), the innermost placental layer, has unique properties that allow for a multitude of clinical applications. It is a common misconception that birth-derived tissue products, such as dual-layered dehydrated amnion–amnion graft (dHAAM), are similar regardless of the manufacturing steps. A commercial dHAAM product, Axolotl Biologix DualGraft™, was assessed for biological and mechanical characteristics. Testing of dHAAM included antimicrobial, cellular biocompatibility, proteomics analysis, suture strength, and tensile, shear, and compressive modulus testing. Results demonstrated that the membrane can be a scaffold for fibroblast growth (cellular biocompatibility), containing an average total of 7678 unique proteins, 82,296 peptides, and 96,808 peptide ion variants that may be antimicrobial. Suture strength results showed an average pull force of 0.2 N per dHAAM sample (equating to a pull strength of 8.5 MPa). Tensile modulus data revealed variation, with wet samples showing 5× lower stiffness than dry samples. The compressive modulus and shear modulus displayed differences between donors (lots). This study emphasizes the need for standardized processing protocols to ensure consistency across dHAAM products and future research to explore comparative analysis with other amniotic membrane products. These findings provide baseline data supporting the potential of amniotic membranes in clinical applications. Full article
(This article belongs to the Special Issue Bioinspired and Biogenic Materials for Biomedical and Bioengineering Applications)
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Review

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19 pages, 2174 KiB  
Review
Physiological Roles of Eumelanin- and Melanogenesis-Associated Diseases: A Look at the Potentialities of Engineered and Microbial Eumelanin in Clinical Practice
by Maria Letizia Terranova
Bioengineering 2024, 11(8), 756; https://doi.org/10.3390/bioengineering11080756 - 25 Jul 2024
Viewed by 1873
Abstract
This paper aims to highlight the physiological actions exerted by eumelanin present in several organs/tissues of the human body and to rationalise the often conflicting functional roles played by this biopolymer on the basis of its peculiar properties. Besides pigmentary disorders, a growing [...] Read more.
This paper aims to highlight the physiological actions exerted by eumelanin present in several organs/tissues of the human body and to rationalise the often conflicting functional roles played by this biopolymer on the basis of its peculiar properties. Besides pigmentary disorders, a growing number of organ injuries and degenerative pathologies are presently ascribed to the modification of physiological eumelanin levels in terms of alterations in its chemical/structural features, and of a partial loss or uneven distribution of the pigment. The present review analyses the more recent research dedicated to the physiological and pathological actions of eumelanin and provides an insight into some melanogenesis-associated diseases of the skin, eye, ear, and brain, including the most significant neurodegenerative disorders. Also described are the potentialities of therapies based on the localised supply of exogeneous EU and the opportunities that EU produced via synthetic biology offers in order to redesign therapeutical and diagnostic applications. Full article
(This article belongs to the Special Issue Bioinspired and Biogenic Materials for Biomedical and Bioengineering Applications)
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