Biomedical Materials Expansion in Tissue Regeneration: Material and Tissue Evaluation

Dear Colleagues,

Biological tissue regeneration using biomedical materials such as collagen, gels, ceramics, polymers, and metals is gaining interest. Biomedical materials are appropriately designed to be minimally invasive and endogenously non-toxic; their application promotes tissue regeneration. In vitro evaluations using biomedical materials are important for tissue regeneration. Furthermore, in vivo evaluation using animal models is essential to ensure the safety of biomedical materials for living organisms before clinical trials. Such in vivo research on tissue regeneration using biomedical materials encompasses a wide range of fields, including skin, bone/cartilage, nerve, and fascia/dura mater. The research boundary between medicine and engineering can provide novel, useful treatments, which could be applied to various diseases in the future. The submission of original articles on new biomedical materials, in vivo/in vitro evaluation methods for regenerated tissues, and knowledge on advanced medical care is welcome for this Special Issue. Specific topics of interest are as follows:

• Fabrication and characterization of biomedical materials, with emphasis on biological compatibility tests involving relevant cell types (e.g., stem cells, fibroblasts, osteoblasts).
• In vivo evaluation of the effects of biomedical materials on animal models and in clinical trials, including tissue regeneration (bone, skin, nerve, cartilage, blood vessel, tendon, etc.) and biomedical materials (ceramics, polymers, metals, collagen, gel, etc.).
• Interaction of biomedical materials with cells such as stem cells, fibroblasts, osteoblasts, etc.
• In vitro evaluation of differentiation and proliferation on the surfaces of biomedical materials.
• Functional evaluation of organs and vital tissues organized on/at the surface of biomedical materials.

Prof. Dr. Osamu Yamamoto
Prof. Dr. Takahiro Kawai
Guest Editors

Dr. Satoshi Migita
migita@yz.yamagata-u.ac.jp
Graduate School of Science and Engineering, Yamagata University, Yonezawa 992-8510, Japan
Guest Editor Assistant

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