Dear Colleagues,

Point-of-care biosensor nanodevices have shown tremendous potentialities to revolutionize future personalized health-care diagnostics and therapy practices. With the rapid growth of nanotechnology, there has been an increased interest toward the development of engineered nanomaterials that can be used for triggered interactions with biological surfaces. In particular, nanomaterials-based biosensors play an increasing role in the construction of biosensing systems for different biological molecules (enzymes, antibodies, proteins, etc.).

Functionalized nanomaterials, due to their unique and tunable electrochemical and optical properties, are being used as immobilization platforms, catalytic tools, optical and electroactive labels to enhance biosensing characteristics with the goal to obtain high sensitivity, stability, and selectivity. Nanostructured sensors offer several advantages such as enhanced loading of desired biomolecules due to their larger surface area, the multifunctional properties of nanostructured materials and thus capability for simultaneous measurements of multiple biomarkers, and detection of minute concentration of desired biomolecules.

Based on the design of the nanoplatfom, target recognition can be performed in a biological environment, and the nano–bio interaction can be transduced into amplified readouts. Biosensing applications are intended for nano–bio-interfaces constructed, e.g., with biopolymeric nanostructured materials, two-dimensional nanohybrid membrane-mimetic surfaces, carbon nanomaterials (including nanotubes, nanofibers, graphene sheets, and their derivatives such as graphene oxide), nanostructured metal/metal oxide, plasmonic nanostructures and microfluidic-based systems.  

This Special Issue deals with the fundamentals of nanomaterials-based biosensors, addressing the different components of transducers, such as electrochemical, optical, piezoelectric, thermal, surface plasmon resonance, and their response at the hybrid biointerface.

Prof. Dr. Cristina Satriano
Guest Editor

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• Nanomaterials
• Biomolecule Immobilization
• Nanotechnology
• Electrochemical biosensors
• Optical biosensors
• Acoustic biosensors
• Functionalization
• Nanoparticle