Special Issue "Nano-Biointerface for Biosensing"

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Nanotechnology and Applied Nanosciences".

Deadline for manuscript submissions: closed (31 May 2019).

Special Issue Editor

Prof. Dr. Cristina Satriano
E-Mail Website
Guest Editor
Head of Nano Hybrid BioInterfaces Lab (NHBIL), Department of Chemical Sciences, University of Catania, Catania, Italy
Interests: physical chemistry of surfaces; soft wet hybrid interfaces; biomaterials;sensors; nano- biointerfaces
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Point-of-care biosensor nanodevices have shown tremendous potentialities to revolutionize future personalized health-care diagnostics and therapy practices. With the rapid growth of nanotechnology, there has been an increased interest toward the development of engineered nanomaterials that can be used for triggered interactions with biological surfaces. In particular, nanomaterials-based biosensors play an increasing role in the construction of biosensing systems for different biological molecules (enzymes, antibodies, proteins, etc.).

Functionalized nanomaterials, due to their unique and tunable electrochemical and optical properties, are being used as immobilization platforms, catalytic tools, optical and electroactive labels to enhance biosensing characteristics with the goal to obtain high sensitivity, stability, and selectivity. Nanostructured sensors offer several advantages such as enhanced loading of desired biomolecules due to their larger surface area, the multifunctional properties of nanostructured materials and thus capability for simultaneous measurements of multiple biomarkers, and detection of minute concentration of desired biomolecules.

Based on the design of the nanoplatfom, target recognition can be performed in a biological environment, and the nano–bio interaction can be transduced into amplified readouts. Biosensing applications are intended for nano–bio-interfaces constructed, e.g., with biopolymeric nanostructured materials, two-dimensional nanohybrid membrane-mimetic surfaces, carbon nanomaterials (including nanotubes, nanofibers, graphene sheets, and their derivatives such as graphene oxide), nanostructured metal/metal oxide, plasmonic nanostructures and microfluidic-based systems.  

This Special Issue deals with the fundamentals of nanomaterials-based biosensors, addressing the different components of transducers, such as electrochemical, optical, piezoelectric, thermal, surface plasmon resonance, and their response at the hybrid biointerface.

Prof. Dr. Cristina Satriano
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Nanomaterials
  • Biomolecule Immobilization
  • Nanotechnology
  • Electrochemical biosensors
  • Optical biosensors
  • Acoustic biosensors
  • Functionalization
  • Nanoparticle

Published Papers (12 papers)

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Open AccessEditorial
Special Issue on Nano-Biointerface for Biosensing
Appl. Sci. 2019, 9(21), 4504; https://doi.org/10.3390/app9214504 - 24 Oct 2019
Cited by 2 | Viewed by 408


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Open AccessArticle
Study of a Miniaturizable System for Optical Sensing Application to Human Cells
Appl. Sci. 2019, 9(5), 975; https://doi.org/10.3390/app9050975 - 07 Mar 2019
Cited by 4 | Viewed by 909
Open AccessArticle
Metallic Nanoparticles Obtained via “Green” Synthesis as a Platform for Biosensor Construction
Appl. Sci. 2019, 9(4), 720; https://doi.org/10.3390/app9040720 - 19 Feb 2019
Cited by 18 | Viewed by 1360
Open AccessFeature PaperArticle
A Hybrid Nanoplatform of Graphene Oxide/Nanogold for Plasmonic Sensing and Cellular Applications at the Nanobiointerface
Appl. Sci. 2019, 9(4), 676; https://doi.org/10.3390/app9040676 - 16 Feb 2019
Cited by 10 | Viewed by 1484
Open AccessArticle
Influence of Chip Materials on Charge Generation in Flowing Solution in Nanobiosensors
Appl. Sci. 2019, 9(4), 671; https://doi.org/10.3390/app9040671 - 16 Feb 2019
Cited by 4 | Viewed by 713
Open AccessArticle
Electrochemical Impedance Characterization of Cell Growth on Reduced Graphene Oxide–Gold Nanoparticles Electrodeposited on Indium Tin Oxide Electrodes
Appl. Sci. 2019, 9(2), 326; https://doi.org/10.3390/app9020326 - 17 Jan 2019
Cited by 4 | Viewed by 1507
Open AccessArticle
The Characterisation and Quantification of Immobilised Concanavalin A on Quartz Surfaces Based on The Competitive Binding to Glucose and Fluorescent Labelled Dextran
Appl. Sci. 2019, 9(2), 318; https://doi.org/10.3390/app9020318 - 17 Jan 2019
Cited by 3 | Viewed by 1081
Open AccessArticle
Development of an Electrochemical Biosensor for Rapid and Effective Detection of Pathogenic Escherichia coli in Licorice Extract
Appl. Sci. 2019, 9(2), 295; https://doi.org/10.3390/app9020295 - 15 Jan 2019
Cited by 5 | Viewed by 1351
Open AccessArticle
Study of the Stability of Functionalized Gold Nanoparticles for the Colorimetric Detection of Dipeptidyl Peptidase IV
Appl. Sci. 2018, 8(12), 2589; https://doi.org/10.3390/app8122589 - 12 Dec 2018
Cited by 8 | Viewed by 1239


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Open AccessReview
Biosensor Applications of Electrodeposited Nanostructures
Appl. Sci. 2019, 9(4), 797; https://doi.org/10.3390/app9040797 - 24 Feb 2019
Cited by 11 | Viewed by 1647
Open AccessReview
A Review on Nanoparticles as Boon for Biogas Producers—Nano Fuels and Biosensing Monitoring
Appl. Sci. 2019, 9(1), 59; https://doi.org/10.3390/app9010059 - 25 Dec 2018
Cited by 11 | Viewed by 1481
Open AccessReview
Nanomaterials-Based Electrochemical Sensors for In Vitro and In Vivo Analyses of Neurotransmitters
Appl. Sci. 2018, 8(9), 1504; https://doi.org/10.3390/app8091504 - 01 Sep 2018
Cited by 20 | Viewed by 2095
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