Special Issue "Nanomaterials for Pro-/Anti-Angiogenic Therapies"
Deadline for manuscript submissions: closed (30 April 2020).
Interests: physical chemistry of surfaces; soft wet hybrid interfaces; biomaterials;sensors; nano- biointerfaces
Special Issues and Collections in MDPI journals
Special Issue in Sensors: Multifunctional Materials Sensors for Theranostic Nanomedicine
Special Issue in International Journal of Molecular Sciences: Nanomaterial for Regenerative Medicine
Angiogenesis, the functional formation of new blood vessels from existing vasculature, is also known as one of the hallmarks of diseases, playing a pivotal role in age-related pathologies, arthritis, ischemic heart disease, tumorigenesis and metastasis. Angiogenesis is mediated through several growth factors and angiopoietic hormones. It is well established that impairment in the angiogenesis process can result in various fatal conditions. Among different types of therapeutic strategies, nanotechnology is emerging as a new approach for the treatment of angiogenesis-related diseases. Nanoparticles with tunable size, shape and surface tailoring have been exploited to achieve effective tumor vascular targeting as well as new promising perspectives in the theranostic field of regenerative nanomedicine. As found in several in vitro and in vivo experiments, nanomaterials are efficient in depriving tumor cells from nutrients and oxygen by inhibiting angiogenesis. On the other hand, methods of targeted angiogenesis in the ischemic areas based on functionalized nanoparticles would be very useful as a novel and challenging therapeutic measure.
In this issue, a particular focus is put on these subjects. We welcome articles with a strong physicochemical and materials science focus, dealing with the topics of surface modification of nanomaterials for tunable interaction at the biointerfaces in all aspects related with promoting or depriving angiogenesis processes in pathological conditions.
Prof. Dr. Cristina Satriano
Manuscript Submission Information
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- hybrid nanomaterials
- soft matter
- surface functionalization
- growth factors