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Applied Sciences
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Photobiomodulation and Photodynamic Therapy in Dentistry and Oral Science
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Photobiomodulation and Photodynamic Therapy in Dentistry and Oral Science

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Dentistry and Oral Sciences".

Deadline for manuscript submissions: 20 May 2025 | Viewed by 4129

Special Issue Editors

Dr. Morena Petrini

E-Mail Website
Guest Editor
Department of Medical, Oral and Biotechnological Sciences, University G. d’Annunzio of Chieti-Pescara, 66100 Chieti, Italy
Interests: clinical dentistry; oral surgery; periodontics; dental implantology; photobiomodulation; photodynamic therapy; dental biomaterials; laser therapy; light emitting diodes; temporary anchorage devices (TADs)
Special Issues, Collections and Topics in MDPI journals
Dr. Emira D’Amico

E-Mail Website
Guest Editor Assistant
Department of Medical, Oral and Biotechnological Sciences, Universitity Gabriele d’Annunzio Chieti-Pescara, Chieti, Italy
Interests: oral biology; biomaterials; dental implants; osteogenesis; bone regeneration

Special Issue Information

Dear Colleagues,

This Special Issue aims to update the literature and discover new trends in photobiomodulation and photodynamic therapy in dentistry.

Photodynamic therapy and photobiomodulation have shown very encouraging results in vitro. However, there is still no solid evidence regarding their efficacy in some specific areas of dentistry, such as periodontology. All this arises from the extreme inhomogeneity of the clinical protocols used and described in the literature, making it almost impossible to compare the results in systematic reviews. All types of manuscripts are welcome, ranging from original articles to literature reviews that will address this topic with innovation and accuracy.

Dr. Morena Petrini
Guest Editor

Dr. Emira D’Amico
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • photobiomodulation
  • photodynamic therapy
  • LED
  • LASER
  • light therapy

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Published Papers (2 papers)

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Review

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15 pages, 1174 KiB  
Review
Low-Level Laser Therapy for Tooth Sensitivity after Tooth Bleaching: A Systematic Review
by Paraskevi Giannakopoulou, Chariklia Neophytou, Panagiotis Karakostas, Konstantinos Papadimitriou, Dimitrios Dionysopoulos, Kosmas Tolidis and Sotiria Davidopoulou
Appl. Sci. 2024, 14(17), 8068; https://doi.org/10.3390/app14178068 - 9 Sep 2024
Cited by 1 | Viewed by 2042
Abstract
Tooth bleaching is a popular cosmetic procedure known for its effective whitening results. However, it may cause tooth sensitivity. Various desensitizing therapies, including laser treatments, are used to alleviate pain and improve patient comfort. This study aims to conduct a systematic review to [...] Read more.
Tooth bleaching is a popular cosmetic procedure known for its effective whitening results. However, it may cause tooth sensitivity. Various desensitizing therapies, including laser treatments, are used to alleviate pain and improve patient comfort. This study aims to conduct a systematic review to evaluate the effectiveness of low-level laser therapy for treating tooth sensitivity following bleaching therapy. A comprehensive search was conducted across 13 electronic databases (PubMed, Scopus, ScienceDirect, Google Scholar, Web of Science, Ovid, BMJ evidence-based medicine, proQuest, Greylit.org, Ethos, Livivo, Clinical trials gov, and Meta register of controlled trials) to identify relevant studies according to specific eligibility criteria, following the PRISMA guidelines. Two independent reviewers screened and selected the studies, performed data extraction, and assessed the risk of bias using the revised Cochrane risk-of-bias tool for randomized clinical trials (RCTs). The initial search yielded 2875 articles, which were subsequently screened to remove duplicates. After evaluating 1532 articles based on title and 136 by abstract, 21 studies remained for full-text assessment. Ultimately, only six RCTs met all of the eligibility criteria. The application of low-level laser therapy appears to reduce tooth sensitivity following tooth bleaching. Despite the positive reported effects, further research is necessary to determine the optimal use of low-level laser therapy for effective pain relief. Full article
(This article belongs to the Special Issue Photobiomodulation and Photodynamic Therapy in Dentistry and Oral Science)
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14 pages, 24194 KiB  
Case Report
Antimicrobial Photodynamic Therapy Combined with Photobiomodulation Therapy in Teeth with Asymptomatic Apical Periodontitis: A Case Series
by Francisco Rubio, Josep Arnabat-Domínguez, Eulàlia Sans-Serramitjana, Camila Saa, Kinga Grzech-Leśniak and Pablo Betancourt
Appl. Sci. 2024, 14(20), 9341; https://doi.org/10.3390/app14209341 - 14 Oct 2024
Cited by 2 | Viewed by 1587
Abstract
Introduction: Apical periodontitis (AP) is an inflammatory disease of the periapical tissues that is often asymptomatic and diagnosed through radiographic examination. A challenge in traditional endodontics is disinfection of the root canal system (RCS), which anatomically presents numerous variations, often leading to persistent [...] Read more.
Introduction: Apical periodontitis (AP) is an inflammatory disease of the periapical tissues that is often asymptomatic and diagnosed through radiographic examination. A challenge in traditional endodontics is disinfection of the root canal system (RCS), which anatomically presents numerous variations, often leading to persistent infections. Antimicrobial photodynamic therapy (aPDT) and photobiomodulation therapy (PBMT) offer promising adjuncts, due to their antimicrobial and tissue-healing properties. Objective: The aim of this article was to report five cases of teeth with pulp necrosis and asymptomatic apical periodontitis (AAP) treated with aPDT and PBMT protocols. Materials and Methods: Five cases of pulp necrosis and AAP were treated with conventional endodontic therapy supplemented with aPDT and PBMT. The treatment protocol included chemomechanical preparation (CMP), aPDT using a 660 nm diode laser (DL) with methylene blue (MB) as a photosensitizer (5 min pre-irradiation time), and PBMT using a 940 nm DL. Treatment results were evaluated through cone-beam computed tomography (CBCT)-based evaluation over 1 year of clinical follow-up. Results: All cases showed significant bone regeneration and tissue healing, demonstrating the efficacy of the combination of aPDT and PBMT. Post-operative pain did not occur in any of the patients, suggesting a possible analgesic effect of PBMT. Conclusions: The combination of aPDT and PBMT in endodontic therapy promoted tissue recovery and improved the prognosis of AAP. Further research and randomized control trials are needed to optimize treatment protocols and evaluate the long-term effects. Full article
(This article belongs to the Special Issue Photobiomodulation and Photodynamic Therapy in Dentistry and Oral Science)
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