Pathology Analysis on Redox Imbalance in Neurodegenerative Diseases and Neuropsychiatric Disorders
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (31 May 2022) | Viewed by 8058
Special Issue Editors
Interests: oxidative stress; Lipoproteins; fatty acids; antioxidant; polyphenols
Interests: oxidative stress at the cellular level; natural and synthetic antioxidants; neurodegenerative diseases
Interests: child psychiatry; psychiatry; ADHD; affective disorders; autism spectrum disorder; eating disorders
Special Issue Information
Dear Colleagues,
Oxidative stress (OS) (redox imbalance), is a phenomenon associated with an imbalance between the formation of reactive oxygen and nitrogen species (ROS/RNS) and protective systems/antioxidants in favor of ROS/RNS formation. Mild OS can play a regulatory role in multiple signaling pathways, while large OS causes damage to important biomolecules, organs, and the whole organism. Intermediate OS can induce cell proliferation.
Increased production of ROS/RNS in the body may result from various external factors or internal pathological conditions (mitochondrial dysfunction, chronic inflammation, dysbalance of neurotransmitters in different signaling pathways) that may initiate pathological processes in the organism.
Oxidative stress is thought to play a role in the pathology of neurodegenerative diseases, such as Alzheimer's, Parkinson's, Huntington's disease, multiple sclerosis, and others. The participation of OS in neuropsychiatric disorders (e.g., schizophrenia, depressive disorder, ADHD, bipolar disorder, and autism) are less well studied. It is not clear whether oxidative stress plays a causal role in their pathology or is a consequence of it. We invite you to submit the latest original research and significant results of your scientific work or review articles with a wide community of colleagues with the same or similar interests in the upcoming Special Issue Pathology Analysis on Redox Imbalance in Neurodegenerative Diseases and Neuropsychiatric Disorders. We welcome in vitro and in vivo studies, as well as pre-clinical and clinical studies involving cellular and molecular mechanisms, pathophysiology of the redox imbalance, new markers of oxidative damage, and their use for pharmacotherapeutic studies.
Prof. Dr. Zdeňka Ďuračková
Dr. Ingrid Žitňanová
Dr. Jana Trebatická
Guest Editors
Manuscript Submission Information
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Keywords
- oxidative stress
- ROS/RNS
- antioxidants
- neurodegenerative diseases
- neuropsychiatric disorders
- markers of OS
- cell culture for OS monitoring
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