Nrf2 in Dermatological Pathologies
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: closed (30 September 2018) | Viewed by 17263
Special Issue Editors
Interests: redox medicine; cold physical plasma; reactive oxygen and nitrogen species; redox signaling; wound healing; dermatology
Special Issues, Collections and Topics in MDPI journals
Interests: redox medicine; immunology; cancer; cold physical plasma; reactive oxygen and nitrogen species; redox signaling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This is to announce a forthcoming Special Issue of the journal Antioxidants on the topic “Nrf2 in Dermatological Pathologies”. Skin diseases, such as psoriasis, skin cancers, or chronic wounds, affects millions of people worldwide, and are strong burdens to patients and health care systems. Skin as the largest body organ serve as important environmental and protection barrier against noxae. A broad spectrum of insults are dermatological toxic by catalyzing the production of reactive oxygen species (ROS) and induction of detrimental redox signaling. An overproduction of ROS can mediate cellular damage of biomolecules, opening of cell junctions, inhibition of migration, alteration of survival and apoptotic signals, and activation of pro-inflammatory responses which are mostly contra-protective for a therapeutic intervention. However, ROS also display hormesis like effects in physiological processes, cellular signal transduction, and immune responses. Essential functions are linked to the activation of the transcription factor Nrf2. Numerous studies show its crucial role in skin protection under oxidative conditions. Further exploration of detailed mechanisms of Nrf2 and down-stream signaling and its therapeutic consequences are the subject of intensive research and will be the content of the forthcoming Special Issue.
We invite both high-quality original articles, as well as reviews, from the whole research area that stimulate and contribute to a deeper understanding of Nrf2 in skin diseases, as well as of biochemical and molecular processes in living systems. Potential topics include, but are not limited to the following:
- Dermatological diseases, cancers, chronic wounds etc.
- Pharmacological use of Nrf2 activators
- Structural, functional, biochemical, and molecular oxidative stress-related effects in in vitro and in vivo studies
- Influence of reactive species on cellular and molecular responses during therapeutic processes
- Role of stimuli showing anti-oxidant characteristics
- Mechanisms of action of novel therapeutics
- Prevention and management of diseases
Authors can submit their manuscripts through the Manuscript Tracking System at https://susy.mdpi.com/user/manuscripts/upload?journal=antioxidants. Manuscripts are published upon acceptance, regardless of the Special Issue publication date.
Dr. Anke Schmidt
Dr. Sander Bekeschus
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Nrf2
- Redox signaling
- Skin diseases
- Reactive oxygen species (ROS)
- Wound healing
- Cancer
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