Dietary Antioxidants in the Mediterranean Diet
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References
- Keys, A.; Arvanis, C.; Blackburn, H. Seven Countries: A Multivariate Analysis of Death and Coronary Heart Disease; Harvard University Press: Cambridge, MA, USA, 1980; p. 381. [Google Scholar]
- Trichopoulou, A.; Martínez-González, M.A.; Tong, T.Y.; Forouhi, N.G.; Khandelwal, S.; Prabhakaran, D.; Mozaffarian, D.; De Lorgeril, M. Definitions and potential health benefits of the Mediterranean diet: Views from experts around the world. BMC Med. 2014, 12, 112. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Barbouti, A.; Kanavaros, P.; Kitsoulis, P.; Goulas, V.; Glalaris, D. Olive oil–contained phenolic compounds protect cells against H2O2-induced damage and modulate redox signaling by chelating intracellular labile iron. In Olives and Olive Oil in Health and Disease Prevention, 2nd ed.; Preedy, V., Watson, R., Eds.; Academic Press: Cambridge, MA, USA, 2021; pp. 231–237. [Google Scholar]
- Sies, H. Oxidative Stress: Concept and some Practical Aspects. Antioxidants 2020, 9, 852. [Google Scholar] [CrossRef] [PubMed]
- Forman, H.J.; Davies, K.J.; Ursini, F. How do nutritional antioxidants really work: Nucleophilic tone and para-hormesis versus free radical scavenging in vivo. Free. Radic. Biol. Med. 2014, 66, 24–35. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Halliwell, B.; Gutteridge, J.M.C. Free Radicals in Biology and Medicine; Oxford University Press: Oxford, UK, 2015. [Google Scholar]
- Yubero-Serrano, E.M.; Lopez-Moreno, J.; Gomez-Delgado, F.; Lopez-Miranda, J. Extra virgin olive oil: More than a healthy fat. Eur. J. Clin. Nutr. 2018, 72, 8–17. [Google Scholar] [CrossRef] [Green Version]
- Lozano-Castellón, J.; López-Yerena, A.; Rinaldi de Alvarenga, J.F.; Romero del Castillo-Alba, J.; Vallverdú-Queralt, A.; Escribano-Ferrer, E.; Lamuela-Raventós, R.M. Health-promoting properties of oleocanthal and oleacein: Two secoir-idoids from extra-virgin olive oil. Crit. Rev. Food Sci. Nutr. 2020, 60, 2532. [Google Scholar] [CrossRef]
- Lozano-Castellón, J.; López-Yerena, A.; Olmo-Cunillera, A.; Jáuregui, O.; Pérez, M.; Lamuela-Raventós, R.M.; Vallverdú-Queralt, A. Total Analysis of the Major Secoiridoids in Extra Virgin Olive Oil: Validation of an UHPLC-ESI-MS/MS Method. Antioxidants 2021, 10, 540. [Google Scholar] [CrossRef]
- Jiang, T.A. Health Benefits of Culinary Herbs and Spices. J. AOAC Int. 2019, 102, 395–411. [Google Scholar] [CrossRef] [PubMed]
- Taghouti, M.; Martins-Gomes, C.; Schäfer, J.; Santos, J.A.; Bunzel, M.; Nunes, F.M.; Silva, A.M. Chemical Characterization and Bioactivity of Extracts from Thymus mastichina: A Thymus with a Distinct Salvianolic Acid Composition. Antioxidants 2020, 9, 34. [Google Scholar] [CrossRef] [Green Version]
- Peixoto, J.A.B.; Álvarez-Rivera, G.; Alves, R.C.; Costa, A.S.G.; Machado, S.; Cifuentes, A.; Ibáñez, E.; Oliveira, M.B.P.P. Comprehensive Phenolic and Free Amino Acid Analysis of Rosemary Infusions: Influence on the Antioxidant Potential. Antioxidants 2021, 10, 500. [Google Scholar] [CrossRef]
- Sedej, I.; Sakač, M.; Mandić, A.; Misan, A.; Tumbas, V.; Čanadanović-Brunet, J. Buckwheat (Fagopyrum esculentumMoench) Grain and Fractions: Antioxidant Compounds and Activities. J. Food Sci. 2012, 77, C954–C959. [Google Scholar] [CrossRef]
- Martín-García, B.; Pasini, F.; Verardo, V.; Gómez-Caravaca, A.M.; Marconi, E.; Caboni, M.F.; García, M.; Caravaca, G. Use of Sieving as a Valuable Technology to Produce Enriched Buckwheat Flours: A Preliminary Study. Antioxidants 2019, 8, 583. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Fiedor, J.; Burda, K. Potential Role of Carotenoids as Antioxidants in Human Health and Disease. Nutrients 2014, 6, 466–488. [Google Scholar] [CrossRef] [Green Version]
- Marhuenda-Muñoz, M.; de Alvarenga, J.R.; Hernáez, Á.; Tresserra-Rimbau, A.; Martínez-González, M.; Salas-Salvadó, J.; Corella, D.; Malcampo, M.; Martínez, J.; Alonso-Gómez, Á.M.; et al. High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma. Antioxidants 2021, 10, 473. [Google Scholar] [CrossRef] [PubMed]
- Barbouti, A.; Lagopati, N.; Veroutis, D.; Goulas, V.; Evangelou, K.; Kanavaros, P.; Gorgoulis, V.G.; Galaris, D. Implication of Dietary Iron-Chelating Bioactive Compounds in Molecular Mechanisms of Oxidative Stress-Induced Cell Ageing. Antioxidants 2021, 10, 491. [Google Scholar] [CrossRef]
- Harman, D. Aging: A Theory Based on Free Radical and Radiation Chemistry. J. Gerontol. 1956, 11, 298–300. [Google Scholar] [CrossRef] [Green Version]
- Galaris, D.; Barbouti, A.; Pantopoulos, K. Iron homeostasis and oxidative stress: An intimate relationship. Biochim. Biophys. Acta BBA Bioenerg. 2019, 1866, 118535. [Google Scholar] [CrossRef]
- Barbouti, A.; Doulias, P.T.; Zhu, B.Z.; Frei, B.; Galaris, D. Intracellular iron, but not copper, plays a critical role in hydrogen peroxide-induced DNA Damage. Free Radic. Biol. Med. 2001, 31, 490. [Google Scholar] [CrossRef]
- Barbouti, A.; Amorgianiotis, C.; Kolettas, E.; Kanavaros, P.; Galaris, D. Hydrogen peroxide inhibits caspase-dependent apoptosis by inactivating procaspase-9 in an iron-dependent manner. Free. Radic. Biol. Med. 2007, 43, 1377–1387. [Google Scholar] [CrossRef] [PubMed]
- Melidou, M.; Riganakos, K.; Galaris, D. Protection against nuclear DNA damage offered by flavonoids in cells exposed to hydrogen peroxide: The role of iron chelation. Free. Radic. Biol. Med. 2005, 39, 1591–1600. [Google Scholar] [CrossRef]
- Kitsati, N.; Mantzaris, M.D.; Galaris, D. Hydroxytyrosol inhibits hydrogen peroxide-induced apoptotic signaling via labile iron chelation. Redox. Biol. 2016, 10, 233–242. [Google Scholar] [CrossRef] [Green Version]
- Gerogianni, P.S.; Chatziathanasiadou, M.V.; Diamantis, D.A.; Tzakos, A.G.; Galaris, D. Lipophilic ester and amide derivatives of rosmarinic acid protect cells against H2O2-induced DNA damage and apoptosis: The potential role of intracellular accumulation and labile iron chelation. Redox. Biol. 2018, 15, 548. [Google Scholar] [CrossRef] [PubMed]
- Kitsati, N.; Fokas, D.; Ouzouni, M.-D.; Mantzaris, M.D.; Barbouti, A.; Galaris, D. Lipophilic Caffeic Acid Derivatives Protect Cells against H2O2-Induced DNA Damage by Chelating Intracellular Labile Iron. J. Agric. Food Chem. 2012, 60, 7873–7879. [Google Scholar] [CrossRef] [PubMed]
- Ben-Othman, S.; Jõudu, I.; Bhat, R. Bioactives from Agri-Food Wastes: Present Insights and Future Challenges. Molecules 2020, 25, 510. [Google Scholar] [CrossRef] [Green Version]
- Goulas, V.; Stavrou, K.; Michael, C.; Botsaris, G.; Barbouti, A. The Potential of Sun-Dried Grape Pomace as a Multi-Functional Ingredient for Herbal Infusion: Effects of Brewing Parameters on Composition and Bioactivity. Antioxidants 2021, 10, 586. [Google Scholar] [CrossRef] [PubMed]
- Dermeche, S.; Nadour, M.; Larroche, C.; Moulti-Mati, F.; Michaud, P. Olive mill wastes: Biochemical characterizations and valorization strategies. Process. Biochem. 2013, 48, 1532–1552. [Google Scholar] [CrossRef]
- Hernáez, Á.; Jaramillo, S.; García-Borrego, A.; Espejo-Calvo, J.A.; Covas, M.-I.; Blanchart, G.; de la Torre, R.; Carrasco-Pancorbo, A.; Mesa, M.D.; Fernández-Prior, M.Á.; et al. From Green Technology to Functional Olive Oils: Assessing the Best Combination of Olive Tree-Related Extracts with Complementary Bioactivities. Antioxidants 2021, 10, 202. [Google Scholar] [CrossRef]
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Barbouti, A.; Goulas, V. Dietary Antioxidants in the Mediterranean Diet. Antioxidants 2021, 10, 1213. https://doi.org/10.3390/antiox10081213
Barbouti A, Goulas V. Dietary Antioxidants in the Mediterranean Diet. Antioxidants. 2021; 10(8):1213. https://doi.org/10.3390/antiox10081213
Chicago/Turabian StyleBarbouti, Alexandra, and Vlasios Goulas. 2021. "Dietary Antioxidants in the Mediterranean Diet" Antioxidants 10, no. 8: 1213. https://doi.org/10.3390/antiox10081213