Oxidant/Antioxidant Balance in Animal Nutrition and Health

Dear Colleagues,

Reactive oxygen species (ROS), including free radicals, are mainly generated as normal byproducts of aerobic respiration and energy metabolism. Exposure to ROS appears to be unavoidable for cells, and ROS toxicity is controlled by a complex network of non-enzymatic and enzymatic antioxidants. Therefore, oxidative stress can be defined as any imbalance between the production and detoxification of ROS. The links between oxidative stress and the development of adverse physiological outcomes constitute important issues in animal science. It is well established that animals require optimal conditions in terms of antioxidant protection in order to ensure optimal health conditions. However, the toxicity of ROS is only one aspect of their action in living cells, as the transient generation of ROS within boundaries appears to be essential for maintaining cellular homeostasis. Interestingly, mounting evidence indicates that many cellular processes associated with ROS production and detoxification are quite sensitive to the quantity and variety of nutrients provided in the diet. This recent recognition that precise nutrients have the ability to modulate cellular oxidative conditions has prompted a revolution in the field of nutrition.

The aim of this Special Issue of Antioxidants is to present a collection of the latest findings or review articles on the oxidant/antioxidant balance in animal nutrition and health. In particular, we are focused on the molecular action of specific nutrients in relation to the elaboration of innovative nutritional approaches aiming to modulate physiological oxidative conditions and improve animal health.

We look forward to your contribution.

Dr. Jérôme Lapointe
Guest Editor

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