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Kinases and Phosphatases, Volume 1, Issue 2

2023 June - 3 articles

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Review

19 Citations

6,316 Views

10 Pages

Protein Kinase CK2 and SARS-CoV-2: An Expected Interplay Story

Camila Paz Quezada Meza and
Maria Ruzzene

Kinases Phosphatases2023, 1(2), 141-150;https://doi.org/10.3390/kinasesphosphatases1020009

16 June 2023

Protein kinase CK2 is a Ser/Thr protein kinase that phosphorylates hundreds of substrates mainly related to survival and proliferation pathways. It has long been considered an anti-cancer drug target. However, during the recent COVID-19 pandemic, CK2...

(This article belongs to the Special Issue Past, Present and Future of Protein Kinase CK2 Research)

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Review

63 Citations

14,522 Views

24 Pages

Recent Advancements in Computational Drug Design Algorithms through Machine Learning and Optimization

Soham Choudhuri,
Manas Yendluri,
Sudip Poddar,
Aimin Li and ,
Koushik Mallick,
Saurav Mallik and
Bhaswar Ghosh
+ 2 authors+ 0 author

Kinases Phosphatases2023, 1(2), 117-140;https://doi.org/10.3390/kinasesphosphatases1020008

5 May 2023

The goal of drug discovery is to uncover new molecules with specific chemical properties that can be used to cure diseases. With the accessibility of machine learning techniques, the approach used in this search has become a significant component in...

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Review

7 Citations

7,263 Views

20 Pages

Regulation of Ras-GTPase Signaling and Localization by Post-Translational Modifications

Arathi Nair and
Bhaskar Saha

Kinases Phosphatases2023, 1(2), 97-116;https://doi.org/10.3390/kinasesphosphatases1020007

21 April 2023

Ras, a GTP-GDP binary switch protein, transduces signals from diverse receptors to regulate various signaling networks. Three Ras genes encode for protein isoforms, namely, Harvey Ras (H-Ras), Kirsten Ras (K-Ras, with two splice variants, K-Ras4A and...

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Kinases Phosphatases - ISSN 2813-3757

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