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Pharmacoepidemiology, Volume 1, Issue 3

December 2022 - 2 articles

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Article

9 Citations

5,542 Views

12 Pages

Evaluation of the Effectiveness of Buprenorphine-Naloxone on Opioid Overdose and Death among Insured Patients with Opioid Use Disorder in the United States

Tianyu Sun,
Natallia Katenka,
Stephen Kogut,
Jeffrey Bratberg,
Josiah Rich and
Ashley Buchanan

Pharmacoepidemiology2022, 1(3), 101-112;https://doi.org/10.3390/pharma1030010

24 November 2022

Opioid use disorder (OUD) is a chronic disease requiring long-term treatment and is associated with opioid overdose and increased risk of mortality. However, existing randomized clinical trials focused on short-term treatment engagement and detoxific...

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Brief Report

3 Citations

7,770 Views

12 Pages

Spironolactone Utilization among Patients with Reduced and Preserved Ejection Fraction Heart Failure

Efe Eworuke,
Austin Cosgrove,
Qoua Liang Her,
Jennifer G. Lyons,
Dave Martin and
Sruthi Adimadhyam

Pharmacoepidemiology2022, 1(3), 89-100;https://doi.org/10.3390/pharma1030009

20 October 2022

Background: Spironolactone is a mineralocorticoid receptor antagonist indicated for the management of heart failure with reduced ejection fraction (HFrEF). In a previous clinical trial, spironolactone significantly lowered the incidence of heart fail...

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