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Onco, Volume 2, Issue 4

2022 December - 2 articles

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Article

3,047 Views

14 Pages

Gene Screening in High-Throughput Right-Censored Lung Cancer Data

Chenlu Ke,
Dipankar Bandyopadhyay,
Mario Acunzo and
Robert Winn

Onco2022, 2(4), 305-318;https://doi.org/10.3390/onco2040017

17 October 2022

Background: Advances in sequencing technologies have allowed collection of massive genome-wide information that substantially advances lung cancer diagnosis and prognosis. Identifying influential markers for clinical endpoints of interest has been an...

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Article

6 Citations

4,096 Views

23 Pages

ERBB1/EGFR and JAK3 Tyrosine Kinases as Potential Therapeutic Targets in High-Risk Multiple Myeloma

Fatih M. Uckun and
Sanjive Qazi

Onco2022, 2(4), 282-304;https://doi.org/10.3390/onco2040016

14 October 2022

Our main objective was to identify abundantly expressed tyrosine kinases in multiple myeloma (MM) as potential therapeutic targets. We first compared the transcriptomes of malignant plasma cells from newly diagnosed MM patients who were risk-categori...

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