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BioMedInformatics, Volume 1, Issue 3

December 2021 - 8 articles

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Articles (8)

  • Article
  • Open Access
2 Citations
4,500 Views
10 Pages

Gibbs Free Energy, a Thermodynamic Measure of Protein–Protein Interactions, Correlates with Neurologic Disability

  • Michael Keegan,
  • Hava T. Siegelmann,
  • Edward A. Rietman,
  • Giannoula Lakka Klement and
  • Jack A. Tuszynski

Modern network science has been used to reveal new and often fundamental aspects of brain network organization in physiological as well as pathological conditions. As a consequence, these discoveries, which relate to network hierarchy, hubs and netwo...

  • Article
  • Open Access
5 Citations
3,816 Views
19 Pages

According to the WHO, approximately 50 million people worldwide have dementia and there are nearly 10 million new cases every year. Alzheimer’s disease is the most common form of dementia and may contribute to 60–70% of cases. It has been...

  • Article
  • Open Access
6 Citations
5,556 Views
16 Pages

Electronic health records (EHRs) can be very difficult to analyze since they usually contain many missing values. To build an efficient predictive model, a complete dataset is necessary. An EHR usually contains high-dimensional longitudinal time seri...

  • Article
  • Open Access
17 Citations
7,811 Views
28 Pages

Analyzing Large Microbiome Datasets Using Machine Learning and Big Data

  • Thomas Krause,
  • Jyotsna Talreja Wassan,
  • Paul Mc Kevitt,
  • Haiying Wang,
  • Huiru Zheng and
  • Matthias Hemmje

Metagenomics promises to provide new valuable insights into the role of microbiomes in eukaryotic hosts such as humans. Due to the decreasing costs for sequencing, public and private repositories for human metagenomic datasets are growing fast. Metag...

  • Article
  • Open Access
2,903 Views
11 Pages

Detecting Patient Health Trajectories Using a Full-Body Burn Physiology Model

  • Austin Baird,
  • Adam Amos-Binks,
  • Nathan Tatum,
  • Steven White,
  • Matthew Hackett and
  • Maria Serio-Melvin

A whole-body physiology model of inflammatory burn injury was used to train an algorithm to correctly detect patients’ states. The physiology model of a thermal injury takes the surface area of patient skin burned as an input to the model and respond...

  • Article
  • Open Access
2 Citations
3,716 Views
21 Pages

Sleep deficiency impacts the quality of life and may have serious health consequences in the long run. Questionnaire-based subjective assessment of sleep deficiency has many limitations. On the other hand, objective assessment of sleep deficiency is...

  • Article
  • Open Access
6 Citations
4,786 Views
18 Pages

Today Deep Learning (DL) is state-of-the-art in medical imaging segmentation tasks, including accurate localization of abdominal organs in MRI images. But segmentation still exhibits inaccuracies, which may be due to texture similarities, proximity o...

  • Article
  • Open Access
3,075 Views
11 Pages

Background: Multiple myeloma (MM) is one of the most common cancers of the blood system. N6-methyladenosine (m6A) plays an important role in cancer progression. We aimed to investigate the prognostic relevance of the m6A score in multiple myeloma thr...

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BioMedInformatics - ISSN 2673-7426