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BioMedInformatics, Volume 1, Issue 2

2021 September - 2 articles

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Feature Paper
Review

2 Citations

5,956 Views

13 Pages

Good Statistical Practices for Contemporary Meta-Analysis: Examples Based on a Systematic Review on COVID-19 in Pregnancy

Yuxi Zhao and
Lifeng Lin

BioMedInformatics2021, 1(2), 64-76;https://doi.org/10.3390/biomedinformatics1020005

23 July 2021

Systematic reviews and meta-analyses have been increasingly used to pool research findings from multiple studies in medical sciences. The reliability of the synthesized evidence depends highly on the methodological quality of a systematic review and...

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Article

3 Citations

5,734 Views

17 Pages

Adjusted Sample Size Calculation for RNA-seq Data in the Presence of Confounding Covariates

Xiaohong Li,
Shesh N. Rai,
Eric C. Rouchka,
Timothy E. O’Toole and
Nigel G. F. Cooper

BioMedInformatics2021, 1(2), 47-63;https://doi.org/10.3390/biomedinformatics1020004

29 June 2021

Sample size calculation for adequate power analysis is critical in optimizing RNA-seq experimental design. However, the complexity increases for directly estimating sample size when taking into consideration confounding covariates. Although a number...

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