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Diabetology, Volume 6, Issue 5

May 2025 - 12 articles

Cover Story: This review explores the bidirectional link between ADHD and metabolic disorders such as obesity and diabetes. It highlights shared pathophysiological mechanisms, including dopaminergic dysfunction, HPA axis dysregulation, inflammation, and oxidative stress. Several critical knowledge gaps remain, which should be addressed with future research. This paper underscores the importance of an integrated clinical approach and the establishment of an interdisciplinary care model that brings together paediatricians, psychiatrists, endocrinologists, and nutritionists. Efforts to publish health-related research should be encouraged to raise awareness about the interconnected nature of these diseases. View this paper
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Articles (12)

  • Article
  • Open Access
4,193 Views
23 Pages

A Randomized Controlled Trial in a 14-Month Longitudinal Design to Analyze the Effects of a Peer Support Instant Messaging Service Intervention to Improve Diabetes Self-Management and Support

  • Elisabeth Höld,
  • Ursula Hemetek,
  • Katharina Tremmel,
  • Tatjana Aubram,
  • Johanna Grüblbauer,
  • Martin Wiesholzer,
  • Manuel Schwanda and
  • Stefan Stieger

Background/Objectives: The outcomes of diabetes therapy depend largely on how well patients can implement medical advice in their lives. The main aim of the DiabPeerS study was to evaluate a peer support instant messaging service (IMS) approach to di...

  • Review
  • Open Access
2 Citations
2,896 Views
21 Pages

The global prevalence of obesity and type 2 diabetes has increased considerably in recent decades, primarily due to behavioral changes associated with societal progress, such as increased consumption of high-calorie foods and sedentary lifestyles. Ob...

  • Article
  • Open Access
1,701 Views
11 Pages

Plan, Track, and Live Mindfully: Insights from the Eat Smart, Move More, Prevent Diabetes Program

  • Erin McCallum,
  • Kelly Nordby,
  • Surabhi Aggarwal,
  • Christine Lavelle,
  • Cathy Thomas and
  • Carolyn Dunn

In the United States, at least one in three adults has prediabetes, a condition categorized by blood glucose levels higher than normal but not high enough to be classified as type 2 diabetes. The Centers for Disease Control and Prevention (CDC) recom...

  • Review
  • Open Access
3 Citations
6,817 Views
15 Pages

The Intricate Relationship Between Thyroid Disorders and Type 2 Diabetes—A Narrative Review

  • Dana-Mihaela Tilici,
  • Diana Loreta Paun,
  • Ana Maria Arnautu,
  • Alexandra Mirica,
  • Carmen Duta,
  • Mirona Costea and
  • Cristian Guja

Thyroid disorders (TDs) and diabetes mellitus (DM) represent significant metabolic pathologies with an important global burden. Diabetes, characterized by chronic hyperglycemia, induces widespread dysregulation of lipid, protein, and carbohydrate met...

  • Review
  • Open Access
4 Citations
15,352 Views
21 Pages

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by inattention, impulsivity and/or hyperactivity. In recent years, metabolic alterations, primarily obesity, insulin resistance, and diabetes, have emerged...

  • Article
  • Open Access
1 Citations
3,983 Views
18 Pages

Interplay of PAK1 and CAMKII in Pancreatic Beta Cell Insulin Secretion

  • Nely Gisela López-Desiderio,
  • Genaro Patiño-López,
  • Citlaltépetl Salinas-Lara,
  • Carlos Sánchez-Garibay,
  • Olga Villamar-Cruz,
  • Alonso Vilches-Flores,
  • José de Jesús Peralta-Romero,
  • Leonel Armas-López,
  • Jazmín García-Machorro and
  • Luis Enrique Arias-Romero
  • + 1 author

Background/Objectives: Type 2 diabetes mellitus (T2DM) is a major global health challenge, primarily driven by insulin resistance and beta-cell dysfunction. This study investigated the roles of p21-activated kinase 1 (PAK1) and calcium/calmodulin-dep...

  • Systematic Review
  • Open Access
3 Citations
5,220 Views
20 Pages

Comparative Analysis of Cardiovascular Outcomes in Type 2 Diabetes Patients Engaging in Aerobic, Resistance, and Combined Training: A Systematic Review

  • Sayed Alireza Mousavi Zadeh,
  • Giuseppe Caminiti,
  • Maurizio Aracri,
  • Massimo Pieri,
  • Anna Paola Mitterhofer,
  • Antonino De Lorenzo,
  • Sergio Bernardini,
  • Pasquale Farsetti,
  • Maurizio Volterrani and
  • Rosario Barone
  • + 2 authors

Background: Among individuals with type 2 diabetes (T2D), cardiovascular disease (CVD) is the leading cause of death, demanding prevention approaches. Exercise is a powerful option for non-pharmacological strategies to improve cardiovascular outcomes...

  • Article
  • Open Access
1 Citations
2,222 Views
10 Pages

Eating Disorders in Young Adults and Adults with Type 1 Diabetes Mellitus

  • Andrea Tomás,
  • Tatiana Fernandes and
  • Helena Loureiro

The literature describes an increased risk of eating disorders (EDs) in patients with Type 1 diabetes mellitus (T1DM) compared to the general population. This risk is mainly related to physical and psychosocial problems related to diabetes. EDs shoul...

  • Article
  • Open Access
1,080 Views
14 Pages

Role of Zinc Homeostasis in the Pathogenesis of Diabetic Osteoporosis in Mice

  • Yoshinori Mizuno,
  • Fuka Takeuchi,
  • Marina Morimoto and
  • Yukinori Tamura

Background: Diabetes induces osteoporosis primarily by impairing osteoblast function. Intracellular zinc homeostasis, which is controlled by zinc transporters, plays a significant role in osteoblast differentiation. In the present study, we aimed to...

  • Review
  • Open Access
2,256 Views
21 Pages

Macrophage Dysfunction in Tuberculosis–Diabetes Mellitus Comorbidity: A Scoping Review of Immune Dysregulation and Disease Progression

  • Simone E. Barry,
  • Alice Sawka,
  • Antonietta Maldari,
  • Joseph Inauen,
  • Sam LaBroome and
  • James B. Geake

Background: Tuberculosis (TB) and diabetes mellitus (DM) comorbidity (TB-DM) presents a significant global health challenge, with diabetes increasing susceptibility to TB, worsening clinical outcomes, and impairing immune responses. Among these dysfu...

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Diabetology - ISSN 2673-4540