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Endocrines, Volume 6, Issue 4

2025 December - 8 articles

Cover Story: Adequate sleep plays a crucial role in human health, particularly in cognitive and physiological functions; however, modern lifestyles have led to increased sleep deprivation, associated with health deterioration, including higher incidence of diabetes mellitus and insulin resistance. This review analyzed the relationship between sleep deprivation and insulin resistance, emphasising the metabolic parameters and hormones involved. Overall, the findings consistently showed reduced insulin sensitivity and increased non-esterified fatty acids in sleep-deprived individuals, while hormonal parameters such as cortisol, metanephrines, and normetanephrines showed inconsistent results. While these results support a clear association between sleep deprivation and insulin resistance, further research is needed to clarify the underlying mechanisms. View this paper
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Endocrines - ISSN 2673-396X