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Transplantology, Volume 7, Issue 3

2026 September - 5 articles

Cover Story: Accurate donor-recipient size matching is essential to successful lung transplantation, yet conventional approaches rely largely on population-based estimates, such as predicted total lung capacity and height. These global metrics cannot fully capture individual thoracic anatomy or disease-specific changes in chest geometry. Advances in CT volumetry, image segmentation, radiomics, and machine learning offer new opportunities to directly characterize donor and recipient anatomy and refine compatibility assessment. This review explores the evolution of lung allograft size matching from simplified global metrics toward imaging-based, patient-specific approaches that may ultimately enable more precise donor-recipient matching and improve transplant outcomes. View this paper
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Articles (5)

  • Review
  • Open Access
142 Views
14 Pages

Immunotherapy for Recurrent Hepatocellular Carcinoma After Liver Transplantation: Current Evidence and Challenges

  • Stella Vasileiadou,
  • Stavros Neiros,
  • Filippos F. Karageorgos,
  • Athanasios Kofinas,
  • Ifaistion Palios,
  • Nikolaos Antoniadis,
  • Emmanouil Sinakos and
  • Georgios Tsoulfas

Background/Objectives: Hepatocellular carcinoma (HCC) frequently develops in the set-ting of chronic liver disease, and liver transplantation (LT) represents the most effective curative option for selected patients. Despite advances in patient select...

(This article belongs to the Topic Advances in Gastrointestinal and Liver Disease: From Physiological Mechanisms to Clinical Practice, 2nd Edition)
  • Article
  • Open Access
286 Views
13 Pages

Background: Patients with end-stage kidney disease commonly develop hyperparathyroidism, which may impair muscle strength and physical function. Elevated parathyroid hormone (PTH) levels have been associated with weakness and poor Timed Up and Go (TU...

(This article belongs to the Section Solid Organ Transplantation)
  • Article
  • Open Access
349 Views
15 Pages

Early vs. Late Extubation After Bilateral Lung Transplantation: Predictors and Outcomes

  • Nicolò Sella,
  • Sabrina Congedi,
  • Francesco Monteleone,
  • Angela Bianco,
  • Giordana Coniglio,
  • Alice Perazzolo,
  • Irene Paiusco,
  • Anna Michielin,
  • Giulia Fichera and
  • Annalisa Boscolo
  • + 14 authors

Background: Early extubation after bilateral lung transplantation (LT) may reduce intensive care unit (ICU) complications, but evidence from heterogeneous real-world cohorts and of its impact on mid-term functional recovery remains limited. Methods:...

(This article belongs to the Section Solid Organ Transplantation)
  • Review
  • Open Access
555 Views
13 Pages

Lung Allograft Size Matching in Transplantation: From Global Metrics to Imaging-Based Approaches

  • Tony Boualoy,
  • Dhiaeddine Djabri,
  • Ahmed H. Aly,
  • Ammu V. Alvarez,
  • Matthew C. Henn,
  • Bryan A. Whitson,
  • Peter J. Kneuertz,
  • Yuan Xue,
  • Doug A. Gouchoe and
  • Kukbin Choi

Accurate donor–recipient allograft size matching remains a critical determinant of outcomes in lung transplantation, yet current approaches rely predominantly on predicted total lung capacity (pTLC) and height-based metrics derived from populat...

(This article belongs to the Special Issue Artificial Intelligence in Modern Transplantation)
  • Article
  • Open Access
826 Views
16 Pages

Clinical Impact of De Novo Donor-Specific HLA Antibodies on Early Kidney Allograft Outcomes: A Prospective Single-Center Cohort Study

  • Sebastian Wolf,
  • Teresa Kauke,
  • Dominik Gschwendtner,
  • Michael Hoffmann,
  • Matthias Schrempf,
  • Lena Anthuber,
  • David Pinto and
  • Florian Sommer

Background: De novo donor-specific antibodies (dnDSA) are associated with impaired allograft outcomes and the development of acute and chronic antibody-mediated rejection. However, their clinical impact during the early post-transplant period remains...

(This article belongs to the Section Solid Organ Transplantation)
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Transplantology - ISSN 2673-3943