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Transplantology, Volume 1, Issue 2

2020 December - 7 articles

Cover Story: In the first wave of the Coronavirus pandemic, it was unclear to what extent solid organ transplant (SOT) recipients are at risk for severe complications due to coronavirus disease (COVID-19). The analysis of the first reported cases resulted in the hypothesis that calcineurin inhibitors (CNI) are protective for these patients, modifying morbidity and mortality and possibly also the incidence. COVID-19 in SOT recipients may present with atypical symptoms or even be oligosymptomatic. Maintenance immunosuppression including a CNI appears to prevent the excessive immune response observed in some patients leading to severe stage III COVID-19 (hyperinflammation) with associated increased mortality. View this paper

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Feature Paper
Article

8 Citations

4,567 Views

12 Pages

Psychosocial Dimensions in Hemodialysis Patients on Kidney Transplant Waiting List: Preliminary Data

Yuri Battaglia,
Luigi Zerbinati,
Elena Martino,
Giulia Piazza,
Sara Massarenti,
Alda Storari and
Luigi Grassi

Transplantology2020, 1(2), 123-134;https://doi.org/10.3390/transplantology1020012

15 December 2020

Although the donation rate for deceased and living kidneys has been increasing, the donor organ availability meets only the 30% of kidney needs in Italy. Consequently, hemodialysis patients stay for a long time, an average of 3.2 years, on a waiting...

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Feature Paper
Review

2 Citations

4,970 Views

12 Pages

The Revolution in Indication for Liver Transplantation: Will Liver Metastatic Disease Overcome the End-Stage Liver Disease in the Next Future?

Tommaso Maria Manzia,
Alessandro Parente,
Roberta Angelico,
Carlo Gazia and
Giuseppe Tisone

Transplantology2020, 1(2), 111-122;https://doi.org/10.3390/transplantology1020011

2 December 2020

Indications for liver transplantation (LT) have constantly been evolving during the last few decades due to a better understanding of liver diseases and innovative therapies. Likewise, also the underlying causes of liver disease have changed. In the...

(This article belongs to the Section Solid Organ Transplantation)

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Feature Paper
Case Report

4,237 Views

9 Pages

Surgical Treatment of Severe Bowel Obstruction as a Rare Complication Following Allogenic Hematopoietic Stem Cell Transplantation

Håkon Reikvam,
Tor Henrik Anderson Tvedt,
Silje Johansen,
Hege Aase Setran and
Roald Flesland Havre

Transplantology2020, 1(2), 102-110;https://doi.org/10.3390/transplantology1020010

17 November 2020

Gastrointestinal graft-versus-host disease (GVHD) and cytomegalovirus (CMV) disease are common complications occurring after allogeneic hematopoietic stem cell transplantation (allo-HSCT), and contribute to a high degree of morbidity and mortality as...

(This article belongs to the Section Artificial Organs, Stem Cells and Xenotransplantation)

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Editorial

1 Citations

3,002 Views

5 Pages

Dietary Assessment and Self-Management Using Information Technology in Order to Improve Outcomes in Kidney Transplant Recipients

Fernanda G. Rodrigues,
Martin H. de Borst and
Ita P. Heilberg

Transplantology2020, 1(2), 97-101;https://doi.org/10.3390/transplantology1020009

1 November 2020

Big data and artificial intelligence (AI) will transform the way research in nephrology is carried out and consequently improve the performance of clinical practice in nephrology and transplantation. Managing long-term health outcomes in kidney trans...

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Feature Paper
Review

6,720 Views

12 Pages

Dental Implant Failure Rate and Marginal Bone Loss in Transplanted Patients: A Systematic Review and Meta-Analysis

Marcela Paraizo,
João Botelho,
Vanessa Machado,
José João Mendes,
Ricardo Alves,
Paulo Mascarenhas and
José Maria Cardoso

Transplantology2020, 1(2), 85-96;https://doi.org/10.3390/transplantology1020008

10 October 2020

This systematic review investigates the failure rate and marginal bone loss (MBL) of dental implants placed in patients undergoing solid-organ transplant (SOT) compared to healthy controls. Three databases (PubMed, Web of Sciences, and the Cochrane L...

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Feature Paper
Review

5 Citations

4,617 Views

14 Pages

Transplant Drugs against SARS, MERS and COVID-19

René Hage,
Carolin Steinack,
Fiorenza Gautschi and
Macé M. Schuurmans

Transplantology2020, 1(2), 71-84;https://doi.org/10.3390/transplantology1020007

3 October 2020

There is an urgent need to develop drugs and vaccines to counteract the effects of the new coronavirus SARS-CoV-2 and adequately treat the corona virus disease (COVID-19). As these drugs are still under investigation, research also focuses on existin...

(This article belongs to the Special Issue Solid Organ Transplantation in the Era of COVID-19)

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Feature Paper
Review

7 Citations

4,987 Views

16 Pages

White Adipose Tissue as a Site for Islet Transplantation

Naoaki Sakata,
Gumpei Yoshimatsu and
Shohta Kodama

Transplantology2020, 1(2), 55-70;https://doi.org/10.3390/transplantology1020006

1 September 2020

Although islet transplantation is recognized as a useful cellular replacement therapy for severe diabetes, surgeons face difficulties in islet engraftment. The transplant site is a pivotal factor that influences the engraftment. Although the liver is...

(This article belongs to the Special Issue 2021 Profile Papers by Transplantology’s Editorial Board Members)

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Transplantology - ISSN 2673-3943

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