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Quantum Reports, Volume 5, Issue 3
September 2023 - 5 articles
Cover Story: In the highly orchestrated realm of DNA replication, mismatch repair stands out as an autonomous process, serving as an ideal subject for studying molecular recognition. The enzyme governing mismatch identification transitions through a series of conformational changes. One crucial change involves bifurcation, leading either to mismatch detection or to the validation of the pair. Intriguingly, this pivotal moment is governed by quantum mechanics; it is modeled as a transition from a high-energy quantum state to one of two lower-energy states. This quantum aspect introduces an inherent probability of error, but it also allows for the reduction in mistakes by channeling more energy into the transition, such as through the consumption of two ATP molecules. View this paper
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Quantum Rep. - ISSN 2624-960XCreative Common CC BY license