Skip to Content

Clocks & Sleep, Volume 4, Issue 3

2022 September - 11 articles

Cover Story: The star-shaped glial cells called astrocytes influence sleep through unknown signaling pathways. We propose that astrocytes detect and integrate a neuronal signal that accumulates during wakefulness, thereby leading to an increased sleep drive. The conditional and selective deletion (cKO) of β2-adrenergic receptors in mouse astrocytes increased active-phase siesta duration under baseline conditions and reduced the metrics of sleep drive following sleep deprivation. These findings suggest that noradrenaline is a waking signal that astrocytes transduce into sleep drive. NR = non-REM sleep, R = REM sleep, W = wakefulness, and WT = wild-type mice. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (11)

  • Communication
  • Open Access
4 Citations
4,425 Views
9 Pages

14 September 2022

This study examined the extent to which the dimensions of the five-factor model, Type-D personality, and multidimensional perfectionism were associated with a diurnal preference in the general population. A sample of (N = 864) individuals completed t...

  • Article
  • Open Access
2 Citations
3,757 Views
8 Pages

Effects of One Night of Forced Wakefulness on Morning Resting Blood Pressure in Humans: The Role of Biological Sex and Weight Status

  • Lieve T. van Egmond,
  • Pei Xue,
  • Elisa M. S. Meth,
  • Maria Ilemosoglou,
  • Joachim Engström and
  • Christian Benedict

14 September 2022

Permanent night shift work is associated with adverse health effects, including elevated blood pressure (BP) and hypertension. Here, we examined the BP response to one night of forced wakefulness in a sitting position in a cohort without night shift...

  • Article
  • Open Access
3 Citations
3,112 Views
10 Pages

1 September 2022

Sleep-related metacognitions play a role in the etiology of insomnia and are distressing while falling asleep. Although similar concepts, such as thought suppression, have been studied in the context of dreaming, the relationship between sleep-relate...

  • Article
  • Open Access
2 Citations
6,607 Views
15 Pages

Potential Benefits of Daytime Naps on Consecutive Days for Motor Adaptation Learning

  • Yusuke Murata,
  • Masaki Nishida,
  • Atsushi Ichinose,
  • Shutaro Suyama,
  • Sumi Youn and
  • Kohei Shioda

Daytime napping offers benefits for motor memory learning and is used as a habitual countermeasure to improve daytime functioning. A single nap has been shown to ameliorate motor memory learning, although the effect of consecutive napping on motor me...

  • Article
  • Open Access
5 Citations
5,104 Views
6 Pages

Time Course of Motor Activity Wake Inertia Dissipation According to Age

  • Lorenzo Tonetti,
  • Miranda Occhionero,
  • Marco Fabbri,
  • Sara Giovagnoli,
  • Martina Grimaldi,
  • Monica Martoni and
  • Vincenzo Natale

The time course of motor activity sleep inertia (maSI) dissipation was recently investigated through actigraphy in an everyday life condition from middle childhood to late adulthood. Motor activity sleep inertia was dissipated in 70 min, and the slee...

  • Article
  • Open Access
11 Citations
7,049 Views
7 Pages

NREM Parasomnias: Retrospective Analysis of Treatment Approaches and Comorbidities

  • Naina Limbekar,
  • Jonathan Pham,
  • Rohit Budhiraja,
  • Sogol Javaheri,
  • Lawrence J. Epstein,
  • Salma Batool-Anwar and
  • Milena Pavlova

The aim of this retrospective analysis is to determine the most frequently prescribed medications for the treatment of NREM parasomnias and evaluate reported outcomes. We performed a retrospective chart review of all patients with NREM parasomnia dia...

  • Review
  • Open Access
9 Citations
11,679 Views
16 Pages

The Effect of Light Therapy on Electroencephalographic Sleep in Sleep and Circadian Rhythm Disorders: A Scoping Review

  • Teha B. Pun,
  • Craig L. Phillips,
  • Nathaniel S. Marshall,
  • Maria Comas,
  • Camilla M. Hoyos,
  • Angela L. D’Rozario,
  • Delwyn J. Bartlett,
  • Wendy Davis,
  • Wenye Hu and
  • Christopher J. Gordon
  • + 4 authors

Light therapy is used to treat sleep and circadian rhythm disorders, yet there are limited studies on whether light therapy impacts electroencephalographic (EEG) activity during sleep. Therefore, we aimed to provide an overview of research studies th...

  • Article
  • Open Access
2 Citations
3,771 Views
12 Pages

The current study examined the possible predictors of dropout during a five-week light treatment (LT) with a gradual advance protocol in 93 patients with unipolar non-seasonal depression and evening chronotypes by comparing their clinical characteris...

  • Article
  • Open Access
11 Citations
5,057 Views
14 Pages

Astrocytes influence sleep expression and regulation, but the cellular signaling pathways involved in these processes are poorly defined. We proposed that astrocytes detect and integrate a neuronal signal that accumulates during wakefulness, thereby...

  • Article
  • Open Access
5 Citations
3,614 Views
11 Pages

Adipokines are a growing group of secreted proteins that play important roles in obesity, sleep disturbance, and metabolic derangements. Due to the complex interplay between adipokines, sleep, and metabolic regulation, an integrated approach is requi...

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Clocks & Sleep - ISSN 2624-5175