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ProceedingsProceedings
  • Abstract
  • Open Access

12 September 2024

Biocompatible Pillar[5]arene-Based Ionic Liquids Containing Amino Acid Fragments as Potential Water Treatment Systems †

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A.M. Butlerov Chemical Institute, Kazan Federal University, Kremlyovskaya 18, 420008 Kazan, Russia
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Author to whom correspondence should be addressed.
Presented at the 1st International Online Conference on Biomimetics (IOCB 2024), 15–17 May 2024; Available online: https://sciforum.net/event/IOCB2024.
This article belongs to the Proceedings The 1st International Online Conference on Biomimetics
Ionic liquids (ILs) are a rapidly growing area of technology and materials science due to their unique properties such as adsorption, recyclability, polarity, and thermal and electrochemical stability. Pillar[5]arenes are a new class of molecular receptors that have proven to be effective drug delivery systems by forming “host-guest” complexes and agents for the selective recognition of biopolymers. The development of ILs based on a non-toxic biomimetic macrocyclic pillar[5]arene platform will lead to a new generation of materials with programmable properties. The purpose of this work is the synthesis of new ILs based on decasubstituted pillar[5]arenes with amino acid fragments (glycine, glycylglycine, L-alanine, and L-phenylalanine) and the study of their thermal stability and the effect of substituents and counterions, as well as the absorption of water-soluble pollutants. Melting point determination and simultaneous thermogravimetry (TG) and differential scanning calorimetry (DSC) were used to study the thermal properties of the ILs. UV spectroscopy was applied to study the interaction and absorption of contaminants by ILs.
Replacement of the bromide anion in the pillar[5]arene structure with NTf2 resulted in a more significant decrease in melting point (56–88 °C) compared to the PF6 anion (86–95 °C), which is logically related to the symmetry and density of the molecular packing. The onset of decomposition of the synthesized compounds was established at 240–300 °C. ILs with L-phenylalanine residues showed lower thermal stability and higher melting points compared to smaller fragments (glycine, alanine). The absorption of water-soluble contaminants by ionic liquids was shown to be possible, as expressed by a decrease in optical density.
The obtained results can be applied to the design of novel biomimetic supramolecular materials for substrate recognition and water treatment.

Supplementary Materials

The presentation material of this work is available online at https://www.mdpi.com/article/10.3390/proceedings2024107040/s1.

Author Contributions

Investigation, methodology, writing—original draft preparation and visualization, V.S.; data curation, supervision, editing, funding acquisition, software, A.N.; writing—review and editing, supervision, I.S. All authors have read and agreed to the published version of the manuscript.

Funding

The work was supported by the Russian Science Foundation (No. 23-73-01087), https://rscf.ru/en/project/23-73-01087/ (accessed on 15 May 2024).

Institutional Review Board Statement

Not applicable.

Data Availability Statement

The data presented in this study are available in Supplementary Materials.

Conflicts of Interest

The authors declare no conflict of interest.
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