Tomography, Volume 12, Issue 5
2026 May - 17 articles
Cover Story: Radiation therapy (RT) plays a major role in treating early and locally advanced thoracic cancer. Although survival rates have increased due to the use of modern RT techniques and advances in treatments, RT-induced cardiac toxicity is still a major concern in these patients. Currently, it is unclear what cardiac substructure RT dose is safe, as a wide range of dose–volume parameters have been evaluated in the retrospective studies to date. Furthermore, current approaches for minimizing doses to organs at risk during RT planning use a one-model-fits-all approach, where a standard dose constraint is used to limit RT dose to the whole heart during treatment planning, regardless of baseline risk factor burden or the presumed diversity of relative radiation sensitivity among the cardiac substructures, which is investigated in this pilot study. View this paper
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Tomography - ISSN 2379-139X