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Tomography, Volume 11, Issue 9

September 2025 - 12 articles

Cover Story: Several sequences for magnetization transfer contrast (MTC) imaging are available, ranging from quantitative magnetization transfer (qMT) that yields the macromolecular fraction to simple ratios of signal intensities with and without a magnetization transfer (MT) pulse. Aging muscle undergoes changes including an increase in fibrosis and fiber atrophy; the objective is to evaluate five MTC sequences to study age-related differences in muscle tissue composition. Significant age-related decreases in macromolecular fraction, MTsat, MTR, and MTRcorr were identified. Age-related decreases in MTC may reflect that loss of myofibrillar proteins dominates the increase in collagen with age. The MTsat sequence was identified as clinically relevant in terms of scan time and sensitivity to age-related differences in macromolecular fraction. View this paper
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Articles (12)

  • Article
  • Open Access
2,764 Views
12 Pages

Rethinking MRI Protocols for Pituitary Microadenomas: Prioritizing Non-Contrast Imaging for Safe Follow-Up

  • Fariba Zarei,
  • Farideh Nematollahi,
  • Asadolah Jalil,
  • Banafsheh Zeinali-Rafsanjani and
  • Mahdi Saeedi-Moghadam

12 September 2025

Introduction and Objectives: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has been used as a gold standard in diagnosing and following pituitary microadenomas. However, the use of gadolinium-based contrast agents (GBCAs) involves a...

  • Article
  • Open Access
1,068 Views
15 Pages

Deep Learning-Based Diagnosis of Femoropopliteal Artery Steno-Occlusion Using Maximum Intensity Projection Images of CT Angiography

  • Wonju Hong,
  • Jaewoong Kang,
  • So Eui Kim,
  • Taikyeong Jeong,
  • Chang Jin Yoon,
  • In Jae Lee,
  • Lyo Min Kwon and
  • Bum-Joo Cho

8 September 2025

Background/Objectives: To develop and validate deep learning-based models for detecting significant steno-occlusion (SSO)—defined as luminal narrowing greater than 50%—of the femoropopliteal arteries using maximum intensity projection (MI...

  • Article
  • Open Access
861 Views
17 Pages

5 September 2025

Background/Objectives: Several sequences for magnetization transfer contrast (MTC) imaging are available, from indices of MTC ranging from quantitative magnetization transfer (qMT) that yields the macromolecular fraction to simple ratios of signal in...

  • Review
  • Open Access
1,536 Views
15 Pages

Bone Evaluation with Micro Finite Element Analysis in Animal Models

  • Behnam Namiranian,
  • Kenichiro Doi,
  • Salem Alenezi,
  • Sameer B. Shah,
  • Saeed Jerban and
  • Eric Y. Chang

1 September 2025

Micro-computed tomography (micro-CT) is a commonly used tool for bone evaluation in animal model research. Micro-scale finite element analysis (µFEA) has been proposed to account for different loading scenarios, detailed three-dimensional (3D)...

  • Article
  • Open Access
1,034 Views
11 Pages

Correlations of Lumbar Interspinous Distance with Neuroforaminal Dimensions, Disc Space Height, and Patient Demographic Factors

  • Carson Cummings,
  • Zachary Brandt,
  • Kai Nguyen,
  • Asael Isaac,
  • Jean-Carlos Gutierrez,
  • Ashley Kempf,
  • David Cheng,
  • Joel D. Carson,
  • Emily Novak and
  • Jacob Razzouk
  • + 2 authors

Background/Objectives: A thorough understanding of spinal anatomy is essential for diagnostic assessment and surgical intervention. Interspinous distance (ISD), neuroforaminal dimensions (NFDs), and disc space height (DSH) have each been studied sepa...

  • Article
  • Open Access
1 Citations
865 Views
24 Pages

Background: The COVID-19 pandemic has claimed thousands of lives worldwide. While infection rates have declined in recent years, emerging variants remain a deadly threat. Accurate diagnosis is critical to curbing transmission and improving treatment...

  • Article
  • Open Access
1,897 Views
11 Pages

Background: Thoracic kyphosis has been increasingly associated with altered intra-abdominal and diaphragmatic dynamics, potentially contributing to gastroesophageal reflux disease (GERD) and hiatal hernia (HH). While previous studies have shown a rel...

  • Article
  • Open Access
1,623 Views
11 Pages

Validation of a Newly Developed Assessment Tool for Point-of-Care Ultrasound of the Thorax in Healthy Volunteers (VALPOCUS)

  • Patrick Hoffmann,
  • Tobias Hüppe,
  • Nicolas Poncelet,
  • Julius J. Weise,
  • Ulrich Berwanger and
  • David Conrad

Objectives: Point-of-care ultrasound (POCUS) has become an integral part of emergency, intensive care, and perioperative medicine. However, the training and subsequent evaluation of POCUS users are still not standardized. The aim of the study was to...

  • Review
  • Open Access
2 Citations
1,538 Views
23 Pages

Leveraging Multimodal Foundation Models in Biliary Tract Cancer Research

  • Yashbir Singh,
  • Jesper B. Andersen,
  • Quincy A. Hathaway,
  • Diana V. Vera-Garcia,
  • Varekan Keishing,
  • Sudhakar K. Venkatesh,
  • Sara Salehi,
  • Davide Povero,
  • Michael B. Wallace and
  • Gregory J. Gores
  • + 4 authors

This review explores how multimodal foundation models (MFMs) are transforming biliary tract cancer (BTC) research. BTCs are aggressive malignancies with poor prognosis, presenting unique challenges due to difficult diagnostic methods, molecular compl...

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Tomography - ISSN 2379-139X