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Tomography, Volume 11, Issue 11

2025 November - 14 articles

Cover Story: Prostate multiparametric MRI (mpMRI) frequently reveals incidental extraprostatic findings in addition to its primary role in assessing suspected prostate cancer. However, the true extent, clinical relevance, and practical implications of these findings in everyday reporting remain insufficiently characterized. This study retrospectively analyzes 607 prostate mpMRI examinations performed at a tertiary care center to systematically record and classify incidental extraprostatic findings by frequency and clinical significance. By relating these findings to patient age, organ system, and clinical context, the study aims to clarify which incidental findings warrant further diagnostic or therapeutic action and to derive practical recommendations for structured radiological reporting and patient management. View this paper
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Articles (14)

  • Article
  • Open Access
4 Citations
2,154 Views
13 Pages

Multimodal CT and MRI Radiomics Integrated with Clinical Models Predict Pathological Complete Response in ESCC Following Neoadjuvant Immunochemotherapy

  • Longgao Liu,
  • Chufeng Zeng,
  • Lizhi Liu,
  • Shumin Zhou,
  • Weihua Wu,
  • Peng Lin,
  • Jianhua Fu,
  • Tiehua Rong,
  • Xu Zhang and
  • Xiaodong Su

19 November 2025

Background: This research focused on evaluating the utility of multimodal radiomics integrated with machine learning to predict pathological complete response (pCR) in a prospective cohort of esophageal squamous cell carcinoma (ESCC) patients undergo...

  • Article
  • Open Access
1,195 Views
15 Pages

14 November 2025

Background: Preoperative evaluation in bariatric surgery aims to minimize perioperative risks and identify comorbid abdominal pathologies that may influence surgical planning. The role of routine abdominal ultrasonography (USG) remains debatable. Met...

  • Article
  • Open Access
2,013 Views
13 Pages

13 November 2025

Rationale and Objective: Medical imaging, particularly computed tomography (CT), is the largest man-made contributor to collective radiation exposure. This study compares methods for assessing CT radiation dose, focusing on thoracic examinations. Pop...

  • Article
  • Open Access
1,988 Views
18 Pages

Prediction of Microsatellite Instability in Colorectal Cancer Using Two Internally Validated Radiomic Models

  • Antonio Galluzzo,
  • Ginevra Danti,
  • Linda Calistri,
  • Diletta Cozzi,
  • Daniele Lavacchi,
  • Daniele Rossini,
  • Lorenzo Antonuzzo,
  • Sebastiano Paolucci,
  • Francesca Castiglione and
  • Vittorio Miele
  • + 2 authors

13 November 2025

Objectives: To develop two different radiomic models based on preoperative contrast-enhanced computed tomography (PP CT) to predict microsatellite instability (MSI) in patients with colorectal cancer (CRC) before surgery. Methods: PP CT scans of 115...

(This article belongs to the Section Abdominal Imaging)
  • Article
  • Open Access
1 Citations
1,524 Views
23 Pages

Photon-Counting Micro-CT for Bone Morphometry in Murine Models

  • Rohan Nadkarni,
  • Zay Yar Han,
  • Alex J. Allphin,
  • Darin P. Clark,
  • Alexandra Badea and
  • Cristian T. Badea

13 November 2025

Background/Objectives: This study evaluates photon-counting CT (PCCT) for the imaging of mouse femurs and investigates how APOE genotype, sex, and humanized nitric oxide synthase (HN) expression influence bone morphology during aging. Methods: A cust...

  • Review
  • Open Access
7 Citations
10,897 Views
38 Pages

Spontaneous Pneumothorax: A Review of Underlying Etiologies and Diagnostic Imaging Modalities

  • Rupali Jain,
  • Vinay Kandula,
  • Drew A. Torigian and
  • Achala Donuru

7 November 2025

This review focuses on the diverse etiologies of secondary spontaneous pneumothorax (SSP) and the crucial role of imaging in their diagnosis. Unlike primary spontaneous pneumothorax (PSP), which is typically due to ruptured blebs, SSP results from a...

(This article belongs to the Section Cardiovascular Imaging)
  • Article
  • Open Access
1 Citations
1,844 Views
11 Pages

5 November 2025

Purpose: To compare retinal thickness measurements obtained with the Optos Monaco and Heidelberg Spectralis optical coherence tomography (OCT) systems across 9 Early Treatment Diabetic Retinopathy Study (ETDRS) sectors in a cohort comprising normal e...

  • Article
  • Open Access
4 Citations
1,286 Views
19 Pages

30 October 2025

Objectives: Kidneytumors, particularly renal cell carcinoma (RCC), represent a critical public health concern due to their prevalence and the severe consequences of late diagnosis. Traditional diagnostic techniques, though widely used, are often limi...

  • Article
  • Open Access
1 Citations
3,447 Views
23 Pages

30 October 2025

Background: Pneumothorax (PTX) requires rapid recognition in emergency and critical care. Lung ultrasound (LUS) offers a fast, radiation-free alternative to computed tomography (CT), but its accuracy is limited by operator dependence. Artificial inte...

  • Article
  • Open Access
1,519 Views
15 Pages

Electron Density and Effective Atomic Number as Quantitative Biomarkers for Differentiating Malignant Brain Tumors: An Exploratory Study with Machine Learning

  • Tsubasa Nakano,
  • Daisuke Hirahara,
  • Tomohito Hasegawa,
  • Kiyohisa Kamimura,
  • Masanori Nakajo,
  • Junki Kamizono,
  • Koji Takumi,
  • Masatoyo Nakajo,
  • Fumitaka Ejima and
  • Takashi Yoshiura
  • + 11 authors

29 October 2025

Objectives: The potential use of electron density (ED) and effective atomic number (Zeff) derived from dual-energy computed tomography (DECT) as novel quantitative imaging biomarkers for differentiating malignant brain tumors was investigated. Method...

  • Article
  • Open Access
3 Citations
2,677 Views
19 Pages

Dose-Dependent Analysis of Image Quality in Pediatric Head CT Scans Across Different Scanners to Optimize Clinical Protocols Using Phantom-Based Assessment

  • Hiroshi Kuwahara,
  • Mitsuaki Ojima,
  • Tsuneko Kawamura,
  • Daisuke Saitou,
  • Kazunari Andou,
  • Eiji Ariga,
  • Kotaro Hasegawa and
  • Michiaki Kai

27 October 2025

Background/Objectives: Optimization of pediatric head computed tomography (CT) protocols is essential to minimize radiation exposure while maintaining diagnostic image quality. Previous studies mainly relied on phantom-based measurements or visual as...

  • Article
  • Open Access
2,641 Views
11 Pages

Prevalence and Significance of Incidental Findings in Multiparametric Magnetic Resonance Imaging of the Prostate

  • David Weiß,
  • Arne Bischoff,
  • Michael Brönnimann,
  • Matteo Haupt and
  • Martin Maurer

23 October 2025

Objective: This study aims to assess the prevalence of clinically significant incidental findings as well as incidental findings of minor clinical significance in multiparametric MRI (mpMRI) of the prostate. Materials and Methods: A retrospective ana...

  • Article
  • Open Access
2 Citations
2,074 Views
17 Pages

22 October 2025

Background/Objectives: Cerebral blood flow (CBF) and cerebral blood volume (CBV) are critical perfusion metrics in diagnosing ischemic stroke. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) enables the evaluation of these cerebral per...

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Tomography - ISSN 2379-139X