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Journal of Imaging, Volume 7, Issue 6
June 2021 - 10 articles
Cover Story: The observation of cancerous cells is of high importance for many areas, not least to test new therapies. Many aspects can be observed, like migration of cells, response to a certain chemotherapy, or the actual shape of a cell and its nucleus. Electron microscopes allow the observation of cells with exquisite detail in three dimensions, which at the same time demands sophisticated methodologies to automate tasks like detection, segmentation and visualisation of volumetric surfaces. This paper describes an algorithm to automatically detect individual instances of three dimensional HeLa cells, from an Electron Microscope dataset, to the volumetric surface of the plasma membrane and nuclear envelope for each of the cells detected. View this paper
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