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Journal of Fungi, Volume 10, Issue 2

2024 February - 74 articles

Cover Story: Aspergillus fumigatus causes a spectrum of infections in patients post lung transplant or with chronic lung disease, ranging from allergic reactions through colonisation to invasive infections. It is also known to precipitate chronic lung allograft dysfunction by interacting with the lung transplant cells and stimulating an immune response. Whilst the host immune function is known to influence the clinical phenotype, genetic variations between different A. fumigatus strains can also play a role. Multi-locus microsatellite typing (MLMT) is the most discriminatory and reproducible genotyping method for A. fumigatus, and it has shown that certain genotypes are associated with certain clinical phenotypes. The aim of this study was to determine the relationship between A. fumigatus genotypes and clinical phenotypes. View this paper
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J. Fungi - ISSN 2309-608X