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JCDDJournal of Cardiovascular Development and Disease
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13 November 2026

14 Pages

A Practical Approach to Exercise in Hypertrophic Cardiomyopathy

,
,
and
1
Department of Kinesiology, University of Virginia School of Education and Human Development, Charlottesville, VA 22903, USA
2
Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA 22904, USA
*
Author to whom correspondence should be addressed.
J. Cardiovasc. Dev. Dis.2026, 13(11), 593;https://doi.org/10.3390/jcdd13110593
This article belongs to the Special Issue Hypertrophic Cardiomyopathy: Genetics, Mechanisms and Therapies
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Abstract

The relationship between exercise and hypertrophic cardiomyopathy (HCM) has evolved over the past decade as a result of updated safety evidence and data supporting the beneficial role of exercise training in HCM patients. Heterogeneity in disease severity precludes a one-size-fits-all exercise prescription, necessitating individualized approaches to exercise testing and exercise prescriptions. This review aims to detail the existing body of literature regarding exercise in HCM as well as outline a practical approach to prescribing exercise in these patients.

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