Hypertrophic Cardiomyopathy: Genetics, Mechanisms and Therapies

Dear Colleagues,

The Journal of Cardiovascular Development and Disease is launching a Special Issue titled “Hypertrophic Cardiomyopathy: Genetics, Mechanisms and Therapies”. We are privileged to be caring for patients with hypertrophic cardiomyopathy (HCM) and to be studying this condition during a period of remarkable progress in both clinical management and scientific understanding.

Advances in precise genetic diagnostics, improvements in imaging, and the development of targeted medical therapies, including cardiac myosin inhibitors and emerging gene therapies, are transforming the landscape of HCM care. These innovations not only improve symptoms but also hold promise for altering the course of disease. Continued progress in risk stratification, including the growing role of artificial intelligence, is further refining clinical decision-making. Important developments are also underway in the management of atrial fibrillation and heart failure in the context of HCM.

For this Special Issue, we invite you to submit your original research articles and reviews. The aim is to provide a clear and comprehensive update on advances in HCM, encompassing mechanistic insights and contemporary approaches to diagnosis and management.

We look forward to receiving your contributions.

Dr. Shepard Weiner
Dr. Lusha W. Liang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access monthly journal published by MDPI.

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