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Journal of Cardiovascular Development and Disease, Volume 1, Issue 2

September 2014 - 2 articles

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Article

7,592 Views

14 Pages

Sox9- and Scleraxis-Cre Lineage Fate Mapping in Aortic and Mitral Valve Structures

Blair F. Austin,
Yuki Yoshimoto,
Chisa Shukunami and
Joy Lincoln

J. Cardiovasc. Dev. Dis.2014, 1(2), 163-176;https://doi.org/10.3390/jcdd1020163

23 September 2014

Heart valves are complex structures composed of a heterogeneous population of valve interstitial cells (VICs), an overlying endothelium and highly organized layers of extracellular matrix. Alterations in valve homeostasis are characteristic of dysfun...

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Article

4 Citations

7,361 Views

17 Pages

Characterization of Dermal Fibroblasts as a Cell Source for Pediatric Tissue Engineered Heart Valves

Monica M. Fahrenholtz,
Huiwen Liu,
Debra L. Kearney,
Lalita Wadhwa,
Charles D. Fraser and
K. Jane Grande-Allen

J. Cardiovasc. Dev. Dis.2014, 1(2), 146-162;https://doi.org/10.3390/jcdd1020146

26 August 2014

There is continued debate regarding the appropriate cell type to replace valvular interstitial cells (VICs) in tissue engineered heart valves (TEHVs), particularly for pediatric patients. In this work, neonatal human dermal fibroblasts (nhDFFs) were...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425|Creative Common CC BY license

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