Skip to Content

Toxics, Volume 8, Issue 1

2020 March - 20 articles

Cover Story: Toxic environmental chemicals can cause functional perturbation of the human gut microbiome, thereby potentially leading to human diseases. The establishment of gut microbiome toxicity links the toxic effects of various environmental agents with microbiota-associated diseases, calling for more comprehensive toxicity assessment. View this paper.
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (20)

  • Review
  • Open Access
106 Citations
18,549 Views
18 Pages

Gut Microbiome Toxicity: Connecting the Environment and Gut Microbiome-Associated Diseases

  • Pengcheng Tu,
  • Liang Chi,
  • Wanda Bodnar,
  • Zhenfa Zhang,
  • Bei Gao,
  • Xiaoming Bian,
  • Jill Stewart,
  • Rebecca Fry and
  • Kun Lu

12 March 2020

The human gut microbiome can be easily disturbed upon exposure to a range of toxic environmental agents. Environmentally induced perturbation in the gut microbiome is strongly associated with human disease risk. Functional gut microbiome alterations...

  • Article
  • Open Access
28 Citations
6,048 Views
15 Pages

Concentration- and Time-Dependent Effects of Benzalkonium Chloride in Human Lung Epithelial Cells: Necrosis, Apoptosis, or Epithelial Mesenchymal Transition

  • Sou Hyun Kim,
  • Doyoung Kwon,
  • Seunghyun Lee,
  • Seung Won Son,
  • Jung-Taek Kwon,
  • Pil-Je Kim,
  • Yun-Hee Lee and
  • Young-Suk Jung

2 March 2020

Benzalkonium chloride (BAC), an antimicrobial agent in inhalable medications and household sprays, has been reported to be toxic to pulmonary organs. Although cell membrane damage has been considered as the main cytotoxic mechanism of BAC, its concen...

  • Article
  • Open Access
37 Citations
5,827 Views
14 Pages

A Comparison of the Nephrotoxicity of Low Doses of Cadmium and Lead

  • Soisungwan Satarug,
  • Glenda C. Gobe,
  • Pailin Ujjin and
  • David A. Vesey

2 March 2020

Environmental exposure to moderate-to-high levels of cadmium (Cd) and lead (Pb) is associated with nephrotoxicity. In comparison, the health impacts of chronic low-level exposure to Cd and Pb remain controversial. The aim of this study was to therefo...

  • Communication
  • Open Access
13 Citations
4,504 Views
8 Pages

1 March 2020

In the fish embryo toxicity (FET) test with zebrafish (Danio rerio) embryos, 3,4-dichloroaniline (3,4-DCA) is often employed as a positive control substance. Previous studies have characterized bioconcentration and transformation of 3,4-DCA in this t...

  • Communication
  • Open Access
30 Citations
5,702 Views
10 Pages

22 February 2020

Mercury (Hg) contamination in soil and forage plants is toxic to ecosystems, and artisanal and small-scale gold mining (ASGM) is the main source of such pollution in the Bombana area of Indonesia. Hg contamination in soil and forage plants was invest...

  • Communication
  • Open Access
32 Citations
5,036 Views
8 Pages

15 February 2020

Microplastics (MPs) are emerging pollutants, which are considered ubiquitous in aquatic ecosystems. The effects of MPs on aquatic biota are still poorly understood, and consequently, there is a need to understand the impacts that MPs may pose to orga...

  • Article
  • Open Access
12 Citations
3,637 Views
10 Pages

Biomonitoring of Trace Elements in Subjects Living Near a Hazardous Waste Incinerator: Concentrations in Autopsy Tissues

  • Francisco García,
  • Montse Marquès,
  • Eneko Barbería,
  • Pilar Torralba,
  • Inés Landin,
  • Carlos Laguna,
  • José L. Domingo and
  • Martí Nadal

11 February 2020

The only hazardous waste incinerator (HWI) in Spain started to operate in 1999. Twenty years later, the levels of 11 trace elements (As, Be, Cd, Cr, Hg, Mn, Ni, Pb, Sn, Tl and V) were analyzed in five different autopsy tissues (kidney, liver, brain,...

  • Article
  • Open Access
11 Citations
3,957 Views
15 Pages

Potential of Inactivated Bifidobacterium Strain in Attenuating Benzo(A)Pyrene Exposure-Induced Damage in Colon Epithelial Cells In Vitro

  • Mengfan Xu,
  • Lili Fu,
  • Junwen Zhang,
  • Tao Wang,
  • Junfeng Fan,
  • Baoqing Zhu,
  • Piotr Dziugan,
  • Bolin Zhang and
  • Hongfei Zhao

11 February 2020

Long-term exposure to benzo(a)pyrene (BaP) poses a serious genotoxic threat to human beings. This in vitro study investigated the potential of inactivated Bifidobacterium animalis subsp. lactis BI-04 in alleviating the damage caused by BaP in colon e...

  • Article
  • Open Access
19 Citations
4,328 Views
20 Pages

11 February 2020

In order to assess the environmental risk of a pharmaceutical, information is needed on the sorption of the compound to solids. Here we use a high-quality database of measured sorption coefficients, all determined following internationally recognised...

  • Article
  • Open Access
35 Citations
5,456 Views
10 Pages

Enchytraeus crypticus Avoid Soil Spiked with Microplastic

  • Stephan Pflugmacher,
  • Johanna H. Huttunen,
  • Marya-Anne von Wolff,
  • Olli-Pekka Penttinen,
  • Yong Jun Kim,
  • Sanghun Kim,
  • Simon M. Mitrovic and
  • Maranda Esterhuizen-Londt

10 February 2020

Microplastics (MPs) of varying sizes are widespread pollutants in our environment. The general opinion is that the smaller the size, the more dangerous the MPs are due to enhanced uptake possibilities. It would be of considerably ecological significa...

  • Article
  • Open Access
19 Citations
6,788 Views
17 Pages

5 February 2020

Cigarette smoking (CS) causes significant morbidity worldwide, attributed to the numerous toxicants generated by tobacco combustion. Electronic cigarettes (ECIG) and heated tobacco products (HTP) are considered alternative smoking/vaping products tha...

  • Article
  • Open Access
92 Citations
23,259 Views
19 Pages

Analysis of Cannabinoid-Containing Fluids in Illicit Vaping Cartridges Recovered from Pulmonary Injury Patients: Identification of Vitamin E Acetate as a Major Diluent

  • Bryan Duffy,
  • Lingyun Li,
  • Shijun Lu,
  • Lorie Durocher,
  • Mark Dittmar,
  • Emily Delaney-Baldwin,
  • Deepika Panawennage,
  • David LeMaster,
  • Kristen Navarette and
  • David Spink

24 January 2020

Beginning in June of 2019, there was a marked increase in reported cases of serious pulmonary injury associated with vaping. The condition, referred to as e-cigarette or vaping product use-associated lung injury (EVALI), does not appear to involve an...

  • Article
  • Open Access
14 Citations
3,912 Views
16 Pages

22 January 2020

Few studies have measured pyrethroid residue concentrations in food items consumed by adults in their daily environments. In a further analysis of study data, the objectives were to determine pyrethroid residue levels in single, solid food items cons...

  • Review
  • Open Access
66 Citations
13,991 Views
7 Pages

Monosodium Glutamate (MSG)-Induced Male Reproductive Dysfunction: A Mini Review

  • Omowumi T. Kayode,
  • Damilare E. Rotimi,
  • Abolanle A. A. Kayode,
  • Tomilola D. Olaolu and
  • Oluyomi S. Adeyemi

22 January 2020

Reproductive dysfunction is often characterized by malfunction of the reproductive tissues, which may lead to disruption of the synergistic rhythm that should bring about a progression of sexual events and the conception of new life. This may therefo...

  • Article
  • Open Access
5 Citations
4,038 Views
9 Pages

A Method for the Evaluation of Site-Specific Nephrotoxic Injury in the Intact Rat Kidney

  • Joshua Edwards,
  • Michael Kowal,
  • Aaron VanDreel,
  • Peter Lamar and
  • Walter Prozialeck

20 January 2020

In a previously published report we detailed an in situ method to quantify cell death in the renal cortex by perfusing the cell membrane impermeable fluorochrome, ethidium homodimer in situ. The objective of the present study was to use this in situ...

  • Feature Paper
  • Article
  • Open Access
23 Citations
4,307 Views
12 Pages

17 January 2020

Personal care products and cosmetics have been identified as major sources of paraben exposure among humans. However, the contribution of dietary factors has not been well understood. We recruited temple stay participants (n = 25) who followed a stri...

  • Article
  • Open Access
12 Citations
4,950 Views
12 Pages

Multi-Analyte MS Based Investigation in Relation to the Illicit Treatment of Fish Products with Hydrogen Peroxide

  • Federica Dal Bello,
  • Riccardo Aigotti,
  • Michael Zorzi,
  • Valerio Giaccone and
  • Claudio Medana

8 January 2020

Fishery products are perishable due to the action of many enzymes, both endogenous and exogenous. The latter are produced by bacteria that may contaminate the products. When fishes age, there is a massive bacteria growth that causes the appearance of...

  • Article
  • Open Access
30 Citations
4,782 Views
12 Pages

24 December 2019

Indole-3-acetic acid (IAA) is a potential mediator in the protection of plants from copper (Cu) toxicity and the enhancement of Cu tolerance. In this paper, spinach (Spinacia oleracea L.) seedlings were cultivated in soil containing 700 mg kg−1...

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Toxics - ISSN 2305-6304