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Children, Volume 10, Issue 5

May 2023 - 149 articles

Cover Story: Ultra-rapid genomic sequencing is increasingly being used in neonatal and pediatric intensive care settings, demonstrating high diagnostic and clinical utility. Arkell and colleagues conducted focus groups with 19 healthcare professionals (including clinical geneticists, genetic counselors, and intensivists) to explore their experiences with ultra-rapid genomic sequencing, particularly when making treatment decisions. They identified that healthcare professionals find it challenging to set realistic expectations with families regarding the outcomes of ultra-rapid genomic sequencing. These healthcare professionals reported modifying pre-test counseling to include life-limiting diagnoses as a possible test outcome. Healthcare professionals explained that moral distress arose when families and healthcare professionals’ treatment goals were misaligned after a diagnosis was received. View this paper
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Articles (149)

  • Article
  • Open Access
5 Citations
3,491 Views
13 Pages

Comparison between Nasopharyngeal and Saliva Samples for the Detection of Respiratory Viruses in Children with Acute Lower Respiratory Tract Infections: A Pilot Study

  • Danilo Buonsenso,
  • Piero Valentini,
  • Francesco Mariani,
  • Silvia Di Noi,
  • Sofia Mazza,
  • Ivana Palucci,
  • Maurizio Sanguinetti and
  • Michela Sali

Purpose: During the COVID-19 pandemic, the use of salivary swabs (SS) to detect the SARS-CoV-2 virus has been implemented and widely studied in adults and children. However, the role of SS in detecting other common respiratory viruses in children is...

  • Article
  • Open Access
7 Citations
3,015 Views
10 Pages

Comparative Evaluation of Extrusion of Apical Debris in Primary Maxillary Anterior Teeth Using Two Different Rotary Systems and Hand Files: An In Vitro Study

  • Balaji Suresh,
  • Ganesh Jeevanandan,
  • Vignesh Ravindran,
  • Mohammed Mashyakhy,
  • Noura Alessa,
  • Ather Ahmed Syed,
  • Suman Panda,
  • Ali Ahmed Assiry,
  • Prabhadevi C. Maganur and
  • Satish Vishwanathaiah

Successful outcome of pulp therapy depends on good chemomechanical preparation of the canals. This is completed with the help of various upcoming rotary and hand files. However, during this preparation, there might be an apical extrusion of the debri...

  • Review
  • Open Access
3 Citations
3,195 Views
21 Pages

Translating Precision Health for Pediatrics: A Scoping Review

  • Mathushan Subasri,
  • Celine Cressman,
  • Danielle Arje,
  • Leighton Schreyer,
  • Erin Cooper,
  • Komal Patel,
  • Wendy J. Ungar,
  • Melanie Barwick,
  • Avram Denburg and
  • Robin Z. Hayeems

Precision health aims to personalize treatment and prevention strategies based on individual genetic differences. While it has significantly improved healthcare for specific patient groups, broader translation faces challenges with evidence developme...

  • Article
  • Open Access
3 Citations
4,381 Views
14 Pages

Understanding the Family Context: A Qualitative Descriptive Study of Parent and NICU Clinician Experiences and Perspectives

  • Maya Dahan,
  • Leahora Rotteau,
  • Shelley Higazi,
  • Ophelia Kwayke,
  • Giselle Lai,
  • Wendy Moulsdale,
  • Lisa Sampson,
  • Jennifer Stannard,
  • Paige Terrien Church and
  • Karel O’Brien

Enabling individualized decision-making for patients requires an understanding of the family context (FC) by healthcare providers. The FC is everything that makes the family unique, from their names, preferred pronouns, family structure, cultural or...

  • Article
  • Open Access
7 Citations
3,326 Views
20 Pages

Evolution of Youth’s Mental Health and Quality of Life during the COVID-19 Pandemic in South Tyrol, Italy: Comparison of Two Representative Surveys

  • Verena Barbieri,
  • Christian J. Wiedermann,
  • Giuliano Piccoliori,
  • Angelika Mahlknecht,
  • Barbara Plagg,
  • Dietmar Ausserhofer,
  • Ulrike Ravens-Sieberer and
  • Adolf Engl

Background: The coronavirus disease 2019 pandemic has led to an increase in youth mental health problems worldwide. Studies have revealed substantial variation in the incidence of these problems across different regions. Longitudinal studies of child...

  • Case Report
  • Open Access
1,874 Views
7 Pages

Heart Failure Post-SARS-CoV-2 Infection in Children with Duchenne Muscular Dystrophy: The Additive Value of Cardiovascular Magnetic Resonance

  • George Markousis-Mavrogenis,
  • Antonios Belegrinos,
  • Aikaterini Giannakopoulou,
  • Evangelos Karanasios,
  • Vasiliki Vartela,
  • Elephtheria Patsilinakou,
  • Paul Samantis,
  • Roser-Marie Pons,
  • Antigoni Papavasiliou and
  • Sophie I. Mavrogeni

In this case series, we describe the diagnosis of post-COVID-19 myocarditis in asymptomatic patients with Duchenne Muscular Dystrophy (DMD) and a mild COVID-19 disease course. These patients were referred for CMR due to electrocardiographic and echoc...

  • Article
  • Open Access
5 Citations
2,402 Views
12 Pages

Factors Associated with Atopic Dermatitis among Children Aged 6 to 14 Years in Alimosho Local Government, Lagos, Nigeria

  • Olubunmi A. Kayode,
  • Charlotte M. Mokoatle,
  • Phoka C. Rathebe and
  • Thokozani P. Mbonane

There has been a rise in the prevalence of atopic dermatitis (AD) globally, especially in low-and middle-income countries such as Nigeria. The condition has been linked to genetic predisposes, living conditions, and environmental factors. Environment...

  • Article
  • Open Access
9 Citations
4,102 Views
13 Pages

Clinical and Functional Characteristics of a New Phenotype of SMA Type I among a National Sample of Spanish Children: A Cross-Sectional Study

  • Beatriz de-Andrés-Beltrán,
  • Javier Güeita-Rodríguez,
  • Domingo Palacios-Ceña and
  • Ángel Luis Rodríguez-Fernández

Spinal Muscular Atrophy (SMA) type I has classically presented extremely severe clinical features. New pharmacological treatments have led to a new phenotype of SMA. The aim of this study was to describe the current health and functional status of ch...

  • Article
  • Open Access
3 Citations
4,891 Views
13 Pages

Prevalence and Predictors of Alcohol Use among School-Going Adolescents in Panama: A Population-Based Cross-Sectional Study

  • Paul Obeng,
  • Francis Sambah,
  • Jacob Owusu Sarfo,
  • Medina Srem-Sai,
  • Newton Isaac Gbordzoe,
  • Richmond Stephen Sorkpor and
  • John Elvis Hagan

This study investigated the prevalence and predictors of alcohol use among school-going-age adolescents in Panama. Using a national school-based cross-sectional survey, data from a proportionate sample of school-going adolescents aged 13–17 yea...

  • Article
  • Open Access
4 Citations
2,415 Views
10 Pages

Quality of Life Outcomes for Patients Who Underwent Conventional Resection and Liver Transplantation for Locally Advanced Hepatoblastoma

  • Zishaan Farooqui,
  • Michael Johnston,
  • Emily Schepers,
  • Nathalie Brewer,
  • Stephen Hartman,
  • Todd Jenkins,
  • Alexander Bondoc,
  • Ahna Pai,
  • James Geller and
  • Gregory M. Tiao

Hepatoblastoma is the most common malignant liver tumor of childhood, with liver transplant and extended resection used as surgical treatments for locally advanced tumors. Although each approach has well-described post-operative complications, qualit...

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Children - ISSN 2227-9067