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Pharmacy, Volume 13, Issue 4

2025 August - 24 articles

Cover Story: Relational pharmacology offers a novel means of understanding how drugs interact across interconnected systems, moving beyond the traditional “one drug–one effect” model. Using systemic maps and visual thinking, this approach helps students to analyze the complexities of polypharmacy, wherein multiple drugs share mechanisms and pathways. By visualizing the body and drug actions as dynamic networks, learners can better identify medication risks, side effects, and therapeutic gaps. Applied to real cases, such as cardiovascular prevention with non-selective antidepressants, systemic maps promote active learning, critical thinking, and meaningful connections between pharmacology, physiology, and biochemistry. This integrative tool prepares future professionals for the complex decision-making required in modern healthcare. View this paper
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Articles (24)

  • Article
  • Open Access
1,743 Views
17 Pages

Detection of Problems Related to Hormonal Contraceptives in Community Pharmacy: Application of a Structured Questionnaire in Women of Childbearing Age

  • Raquel Sicilia-González,
  • Susana Abdala-Kuri,
  • Chaxiraxi Morales-Marrero,
  • Adama Peña-Vera,
  • Alexis Oliva-Martín and
  • Sandra Dévora-Gutiérrez

21 August 2025

The use of hormonal contraceptives is essential to ensure effective and safe contraception. However, factors such as inadequate prescription, poor adherence, or lack of information can lead to drug-related problems (DRPs) and negative outcomes associ...

  • Article
  • Open Access
626 Views
10 Pages

20 August 2025

Background: With increasing involvement of pharmacists in clinical situations and expanding scope of practice, the expectation and management of uncertainty is a desirable component of pharmacy education, leading to improved uncertainty tolerance (UT...

  • Article
  • Open Access
1 Citations
1,420 Views
19 Pages

Developing Soft Skills for Sustainable Community Pharmacy Practice Through a Competency-Based Modular Programme

  • Ivana Zimonjić,
  • Lazar Dražeta,
  • Valentina Marinković and
  • Tatjana Milošević

20 August 2025

This study explored a competency-based soft-skills programme supporting evolving community pharmacy professionals’ roles and sustainable practice in Serbia. Four researchers with academic and practice backgrounds developed the programme using h...

  • Systematic Review
  • Open Access
2 Citations
3,617 Views
17 Pages

19 August 2025

Polypharmacy in older adults increases risks of adverse drug reactions (ADRs), hospitalisations, and mortality. Pharmacist-led interventions using validated tools (e.g., STOPP/START, MAI, STOPPFrail) aim to optimise prescribing, yet their impact on c...

  • Review
  • Open Access
1,914 Views
16 Pages

Analysis of Legislative and Regulatory Frameworks Governing Community Pharmacy in Bulgaria and North Macedonia

  • Anna Todorova,
  • Mariya Ivanova,
  • Magdalena Pesheva,
  • Dijana Miceva and
  • Bistra Angelovska

8 August 2025

The common border between Bulgaria and North Macedonia, alongside the regulatory requirements stemming from Bulgaria’s membership in the European Union, provide grounds for comparing the legislative environment in both countries. This article p...

  • Article
  • Open Access
2,714 Views
13 Pages

The Role of the Clinical Pharmacist in Hospital Admission Medication Reconciliation in Low-Resource Settings

  • Tijana Kovačević,
  • Sonja Nedinić,
  • Vedrana Barišić,
  • Branislava Miljković,
  • Emir Fazlić,
  • Slobodan Vukadinović and
  • Pedja Kovačević

2 August 2025

Medication discrepancies at hospital admission are common and may lead to adverse outcomes. Medication reconciliation is a critical process for minimizing medication discrepancies and medication errors at the time of hospital admission. This study ai...

  • Review
  • Open Access
1 Citations
3,896 Views
62 Pages

1 August 2025

Osteoarthritis (OA) remains a major contributor to pain and disability; however, the current management is largely reactive, focusing on symptoms rather than preventing irreversible cartilage loss. This review first examines the mechanistic foundatio...

  • Review
  • Open Access
3 Citations
10,342 Views
21 Pages

Improving Hemorrhoid Outcomes: A Narrative Review and Best Practices Guide for Pharmacists

  • Nardine Nakhla,
  • Ashok Hospattankar,
  • Kamran Siddiqui and
  • Mary Barna Bridgeman

30 July 2025

Hemorrhoidal disease remains a prevalent yet often overlooked condition, affecting millions worldwide and imposing a substantial healthcare burden. Despite the availability of multiple treatment options, gaps persist in patient education, early sympt...

  • Brief Report
  • Open Access
3,147 Views
8 Pages

Accuracy and Safety of ChatGPT-3.5 in Assessing Over-the-Counter Medication Use During Pregnancy: A Descriptive Comparative Study

  • Bernadette Cornelison,
  • David R. Axon,
  • Bryan Abbott,
  • Carter Bishop,
  • Cindy Jebara,
  • Anjali Kumar and
  • Kristen A. Root

30 July 2025

As artificial intelligence (AI) becomes increasingly utilized to perform tasks requiring human intelligence, patients who are pregnant may turn to AI for advice on over-the-counter (OTC) medications. However, medications used in pregnancy may pose pr...

  • Article
  • Open Access
2,430 Views
13 Pages

29 July 2025

Adverse drug reactions (ADRs) significantly affect patient safety and healthcare spending worldwide. Hospital pharmacists are uniquely positioned to address ADRs due to their crucial role in medication management. However, underreporting remains a gl...

  • Article
  • Open Access
1 Citations
1,477 Views
17 Pages

29 July 2025

The uptake of the COVID-19 and seasonal influenza (SI) vaccines have decreased in Europe and especially in Malta. The present study aimed to investigate the attitudes toward COVID-19 and SI vaccines and determine if individuals perceive that these va...

  • Article
  • Open Access
2,225 Views
13 Pages

Evaluation of Medication Adherence and Appropriateness Among Heart Failure Patients Attending the Cardiac Clinic at a Tertiary Care Hospital: A Cross-Sectional Observational Study

  • Nanayakkara Muhandiramalaya Yasa Kalum Bagyawantha,
  • Isuri Nilnuwani Dangahage,
  • Ghanamoorthy Mayurathan and
  • Weerasinghe Mudiyanselage Suminda Pushpika

27 July 2025

Heart failure is a chronic disease with significantly high morbidity and mortality rates, and a thorough understanding of medication adherence and appropriateness is crucial to ensure effective treatment outcomes. This cross-sectional observational s...

  • Brief Report
  • Open Access
1,112 Views
11 Pages

23 July 2025

A total of 38% of Americans do not meet the Recommended Dietary Allowance (RDA) for calcium including those at risk for osteoporosis. To increase the percentage of patients at risk for osteoporosis who achieve goal calcium RDA intake, a collaborative...

  • Article
  • Open Access
1,360 Views
13 Pages

The Use of RE-AIM to Evaluate a Pharmacist-Led Transitions of Care Service for Multivisit Patients at a Regional Hospital

  • Courtney E. Gamston,
  • Salisa C. Westrick,
  • Mafe Zmajevac,
  • Jingjing Qian,
  • Greg Peden,
  • Dillon Hagan and
  • Kimberly Braxton Lloyd

Pharmacist-led transitions of care (TOC) services decrease preventable hospital readmission. TOC service implementation assessment can inform translation to real-world settings. The purpose of this study was to evaluate the implementation of a TOC se...

  • Review
  • Open Access
6,331 Views
11 Pages

Lysergic Acid Amide (LSA), an LSD Analog: Systematic Review of Pharmacological Effects, Adverse Outcomes, and Therapeutic Potentials

  • Paula S. C. C. Castro,
  • Kae Leopoldo,
  • Maria Olivia Pozzolo Pedro,
  • Juliana Takitane,
  • Henrique Silva Bombana,
  • André Brooking Negrão,
  • Jaqueline R. Scholz and
  • João Maurício Castaldelli-Maia

Objective: To systematically review the scientific literature on lysergic acid amide (LSA), focusing on its physical, neurobiological, and social effects, as well as its potential risks and therapeutic uses. Methods: A systematic review was conducted...

  • Review
  • Open Access
3,562 Views
20 Pages

(1) Background: Patient-centered care for individuals with breast cancer requires multidisciplinary cooperation to ensure the appropriate use of medication and prevent medication-related problems. Pharmaceutical care has been associated with improved...

  • Article
  • Open Access
3,973 Views
16 Pages

Introduction: Chronic pain affects approximately 20% of U.S. adults, imposing significant burdens on individuals and healthcare systems. Medical cannabis has emerged as a potential therapy, yet its impact on healthcare utilization remains unclear. Me...

  • Review
  • Open Access
2,176 Views
17 Pages

Polycystic ovary syndrome (PCOS) is an endocrine disorder prevalent in women of reproductive age, often requiring complex pharmacological management. The heterogeneity of the syndrome and the use of on- and off-label therapeutic agents—ranging...

  • Article
  • Open Access
3 Citations
4,081 Views
17 Pages

Enhancing the Role of Community Pharmacists in Medication Safety: A Qualitative Study of Voices from the Frontline

  • Annesha White,
  • Erika L. Thompson,
  • Solyi Kim,
  • Janice A. Osei,
  • Kimberly G. Fulda and
  • Yan Xiao

Preventable adverse drug events (ADEs) remain a significant threat in community settings, a challenge that is critical in community pharmacy settings where continuity of care and healthcare access can be limited. This qualitative study explored the p...

  • Article
  • Open Access
766 Views
10 Pages

Type II Diabetes Mellitus and COVID-19: Exploring Insulin Management in Patients from Family Medicine Clinics

  • Chinemerem Opara,
  • Annesha White,
  • Kimberly G. Fulda,
  • Somer Blair,
  • Clare Aduwari,
  • Nihitha Nukala and
  • Yan Xiao

The COVID-19 pandemic disrupted routine care for individuals with type 2 diabetes mellitus (T2DM), raising concerns about its impact on glycemic control and medication management. This study evaluated the relationship between insulin use and glycemic...

  • Article
  • Open Access
748 Views
13 Pages

Polysubstance use (PSU) involving marijuana among women of reproductive age (WRA) is linked to psychosocial harm, yet research on the combined effects of marijuana with stimulants, opioids, tobacco, and binge drinking remains limited. The purpose of...

  • Article
  • Open Access
3,005 Views
12 Pages

Relational pharmacology introduces an innovative approach using visual thinking to understand how drugs interact with multiple body systems, addressing the limitations of the traditional “reductionist approach”. While conventional pharmac...

  • Review
  • Open Access
1 Citations
1,621 Views
15 Pages

Historical Process, Status and Future Development of Pharmacovigilance Systems in Chinese Medicine

  • Xue Wang,
  • Yinfeng Wang,
  • Xiaomeng Zhang,
  • Bing Zhang and
  • Zhijian Lin

The definition of pharmacovigilance was first proposed in the 1970s to safeguard public health and the safety of drug use, and to improve the quality of life of patients. China’s traditional medicine has also always contained the idea of vigila...

  • Systematic Review
  • Open Access
2,258 Views
16 Pages

Background: The role of clinical pharmacists in the emergency department continues to gain recognition, particularly during cardiac and trauma resuscitations. However, their contributions to patient outcomes remain unclear. The objective of this scop...

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Pharmacy - ISSN 2226-4787