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Biomolecules, Volume 11, Issue 4
April 2021 - 128 articles
Cover Story: The circadian rhythm in humans is driven by a complex primary transcriptional–translational autoregulatory feedback loop located in suprachiasmatic nucleus in the brain. Evidence suggests that alterations in this system through modern lifestyle, characterized by physical inactivity, overconsumption of food and changes in normal sleep/wake cycle, may have an influence on our metabolic and hormonal health. Time-restricted feeding and exercise have been shown to play a crucial role in resetting the disruptions in circadian processes, making both appropriate nutrition and exercise timing powerful tools to support circadian rhythm and potentially contribute to the prevention of metabolic diseases. However, the potential cause of diseases arising from sleep deprivation may not solely be solved by only treating symptoms rather than eliminating the source of alterations in diurnal rhythmicity. View this paper
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Biomolecules - ISSN 2218-273X