Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2015).
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Sci. Pharm. 2015, 83(2), 221-231; https://doi.org/10.3797/scipharm.1411-14 (registering DOI)
Synthesis and Anti-Platelet Activity of Thiosulfonate Derivatives Containing a Quinone Moiety
Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology, Lviv Polytechnic National University, Bandera Str. 12, 79013, Lviv, Ukraine.
Laboratoire de Pharmaco-Chimie Radicalaire, Institut de Chimie Radicalaire ICR, Faculté de Pharmacie, Aix-Marseille Univ, CNRS, UMR 7273, Bd J. Moulin 27, 13385, Marseille Cedex 05, France.
Educational and Scientific centre “Institute of Biology”, Taras Shevchenko National University of Kyiv, Volodymyrska Str. 64/13, 01601, Kyiv, Ukraine
Authors to whom correspondence should be addressed.
Received: 26 November 2014 / Accepted: 24 February 2015 / Published: 24 February 2015
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Abstract Thiosulfonate derivatives based on quinones were synthesized for studying “structure-activity relationship” compounds with an acylated and a free amino-group. Anti-platelet activity of the synthesized compounds was determined and the influence of substituents on the activity of the derivatives was assessed.
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BOLIBRUKH, K.; POLOVKOVYCH, S.; KHOUMERI, O.; HALENOVA, T.; NIKOLAEVA, I.; SAVCHUK, O.; TERME, T.; VANELLE, P.; LUBENETS, V.; NOVIKOV, V. Synthesis and Anti-Platelet Activity of Thiosulfonate Derivatives Containing a Quinone Moiety. Sci. Pharm. 2015, 83, 221-231.
BOLIBRUKH K, POLOVKOVYCH S, KHOUMERI O, HALENOVA T, NIKOLAEVA I, SAVCHUK O, TERME T, VANELLE P, LUBENETS V, NOVIKOV V. Synthesis and Anti-Platelet Activity of Thiosulfonate Derivatives Containing a Quinone Moiety. Scientia Pharmaceutica. 2015; 83(2):221-231.
BOLIBRUKH, Khrystyna; POLOVKOVYCH, Svyatoslav; KHOUMERI, Omar; HALENOVA, Tetyana; NIKOLAEVA, Irina; SAVCHUK, Olexiy; TERME, Thierry; VANELLE, Patrice; LUBENETS, Vira; NOVIKOV, Volodymyr. 2015. "Synthesis and Anti-Platelet Activity of Thiosulfonate Derivatives Containing a Quinone Moiety." Sci. Pharm. 83, no. 2: 221-231.
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